Viral endothelial dysfunction: A unifying mechanism for COVID-19

M Prasad, M Leon, LO Lerman, A Lerman - Mayo Clinic Proceedings, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
transmissible virus with significant global impact, morbidity, and mortality. The SARS-CoV-2 …

Endothelial dysfunction in SARS-CoV-2 infection

F Nappi, SS Avtaar Singh - Biomedicines, 2022 - mdpi.com
One of the hallmarks of the SARS-CoV-2 infection has been the inflammatory process that
played a role in its pathogenesis, resulting in mortality within susceptible individuals. This …

What is linking COVID-19 and endothelial dysfunction? Updates on nanomedicine and bioengineering from the 2020 AHA Scientific Sessions

J Gambardella, G Santulli - 2021 - academic.oup.com
The 2020 Scientific Sessions of the American Heart Association (AHA) featured 139
presentations of works related to COVID-19. While most of the studies were reporting …

Obesity-related inflammation and endothelial dysfunction in COVID-19: Impact on disease severity

A De Lorenzo, V Estato… - Journal of …, 2021 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic has put into evidence another
pandemic–obesity. Currently, several studies have documented the association between …

Persistent endothelial dysfunction in post-acute COVID-19 syndrome: a case-control study

P Ambrosino, I Calcaterra, A Molino, P Moretta… - Biomedicines, 2021 - mdpi.com
Background: Endothelial dysfunction has a key role in the pathogenesis of coronavirus
disease 2019 (COVID-19) and its disabling complications. We designed a case-control …

The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection

S Pons, S Fodil, E Azoulay, L Zafrani - Critical care, 2020 - Springer
In severe SARS-CoV-2 infections, emerging data including recent histopathological studies
have emphasized the crucial role of endothelial cells (ECs) in vascular dysfunction …

Pulmonary vascular system: A vulnerable target for COVID‐19

J Ai, W Hong, M Wu, X Wei - MedComm, 2021 - Wiley Online Library
The number of coronavirus disease 2019 (COVID‐19) cases has been increasing
significantly, and the disease has evolved into a global pandemic, posing an unprecedented …

Mechanisms of endothelial activation, hypercoagulation and thrombosis in COVID-19: a link with diabetes mellitus

I Valencia, J Lumpuy-Castillo, G Magalhaes… - Cardiovascular …, 2024 - Springer
Early since the onset of the COVID-19 pandemic, the medical and scientific community were
aware of extra respiratory actions of SARS-CoV-2 infection. Endothelitis, hypercoagulation …

Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?

A Huertas, D Montani, L Savale… - European …, 2020 - Eur Respiratory Soc
Coronavirus disease 2019 (COVID-19) represents a public health crisis of pandemic
proportions. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Endothelial dysfunction in Coronavirus disease 2019 (COVID-19): Gender and age influences

G Froldi, P Dorigo - Medical hypotheses, 2020 - Elsevier
Several risk factors are associated with a worse outcome for COVID-19 patients; the most
recognized are demographic characteristics such as older age and male gender, and pre …