A dedicated population for reward coding in the hippocampus
JL Gauthier, DW Tank - Neuron, 2018 - cell.com
The hippocampus plays a critical role in goal-directed navigation. Across different
environments, however, hippocampal maps are randomized, making it unclear how goal …
environments, however, hippocampal maps are randomized, making it unclear how goal …
Different encoding of reward location in dorsal and intermediate hippocampus
Hippocampal place cells fire at specific locations in the environment. They form a cognitive
map that encodes spatial relations in the environment, including reward locations. 1 As part …
map that encodes spatial relations in the environment, including reward locations. 1 As part …
Spatial goal coding in the hippocampal formation
The mammalian hippocampal formation contains several distinct populations of neurons
involved in representing self-position and orientation. These neurons, which include place …
involved in representing self-position and orientation. These neurons, which include place …
Rapid synaptic plasticity contributes to a learned conjunctive code of position and choice-related information in the hippocampus
To successfully perform goal-directed navigation, animals must know where they are and
what they are doing—eg, looking for water, bringing food back to the nest, or escaping from …
what they are doing—eg, looking for water, bringing food back to the nest, or escaping from …
Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal
Hippocampal place cells support reward-related spatial memories by forming a cognitive
map that over-represents reward locations. The strength of these memories is modulated by …
map that over-represents reward locations. The strength of these memories is modulated by …
Navigating for reward
M Sosa, LM Giocomo - Nature Reviews Neuroscience, 2021 - nature.com
An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …
associated with rewards, such as food or a home. Accumulating research has revealed that …
[HTML][HTML] Sublayer-specific coding dynamics during spatial navigation and learning in hippocampal area CA1
The mammalian hippocampus is critical for spatial information processing and episodic
memory. Its primary output cells, CA1 pyramidal cells (CA1 PCs), vary in genetics …
memory. Its primary output cells, CA1 pyramidal cells (CA1 PCs), vary in genetics …
A role for the locus coeruleus in hippocampal CA1 place cell reorganization during spatial reward learning
AM Kaufman, T Geiller, A Losonczy - Neuron, 2020 - cell.com
During spatial learning, hippocampal (HPC) place maps reorganize to represent new goal
locations, but little is known about the circuit mechanisms facilitating these changes. Here …
locations, but little is known about the circuit mechanisms facilitating these changes. Here …
Insensitivity of place cells to the value of spatial goals in a two-choice flexible navigation task
Hippocampal place cells show position-specific activity thought to reflect a self-localization
signal. Several reports also point to some form of goal encoding by place cells. We …
signal. Several reports also point to some form of goal encoding by place cells. We …
Motivational states activate distinct hippocampal representations to guide goal-directed behaviors
PJ Kennedy, ML Shapiro - Proceedings of the National …, 2009 - National Acad Sciences
Adaptive behaviors are guided by motivation and memory. Motivational states specify goals,
and memory can inform motivated behavior by providing detailed records of past …
and memory can inform motivated behavior by providing detailed records of past …