Volatile anesthetics protect the ischemic rabbit myocardium from infarction

DK Cope, KW Impastato, MV Cohen… - The Journal of the …, 1997 - pubs.asahq.org
Background The influence of anesthetic agents on the infarction process in the ischemic
myocardium is unclear. This study evaluated the effects of three intravenous and three …

Cardioprotection by volatile anesthetics

MW Bienengraeber, D Weihrauch, JR Kersten… - Vascular …, 2005 - Elsevier
Preconditioning describes a very powerful endogenous mechanism by which the heart may
be protected against ischemia and reperfusion injury. Transient administration of a volatile …

Mechanisms of cardioprotection by volatile anesthetics

K Tanaka, LM Ludwig, JR Kersten… - The Journal of the …, 2004 - pubs.asahq.org
A RAPIDLY growing body of evidence indicates that volatile anesthetics protect myocardium
against reversible and irreversible ischemic injury. Identifying the mechanisms by which …

Isoflurane, but not Halothane, Induces Protection of Human Myocardium via  Adenosine A1Receptors and Adenosine Triphosphate–sensitive Potassium Channels

AK Roscoe, JD Christensen, C Lynch - The Journal of the American …, 2000 - pubs.asahq.org
Background Volatile anesthetics produce differing degrees of myocardial protection in
animal models of ischemia. The purpose of the current investigation was to determine the …

Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs

WG Toller, JR Kersten, PS Pagel… - The Journal of the …, 1999 - pubs.asahq.org
Background Recent evidence indicates that volatile anesthetics exert protective effects
during myocardial ischemia and reperfusion. The authors tested the hypothesis that …

The role of Volatile Anesthetics in Cardioprotection: a systematic review

NR Van Allen, PR Krafft, AS Leitzke, RL Applegate… - Medical gas …, 2012 - Springer
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in
both clinical and laboratory research and furthermore assesses possible cardiac side effects …

Effects of enflurane, isoflurane, sevoflurane and desflurane on reperfusion injury after regional myocardial ischaemia in the rabbit heart in vivo

B Preckel, W Schlack, T Comfere, D Obal… - British journal of …, 1998 - Elsevier
It is known that volatile anaesthetics protect myocardial tissue against ischaemic and
reperfusion injury in vitro. In this investigation, we have determined the effects of the …

Cardiac pharmacological preconditioning with volatile anesthetics: from bench to bedside?

ML Riess, DF Stowe… - American Journal of …, 2004 - journals.physiology.org
A steadily increasing number of investigations demonstrate that preconditioning with volatile
anesthetics attenuates the deleterious effects of myocardial ischemia and reperfusion injury …

Cardioprotection with volatile anesthetics: mechanisms and clinical implications

SG De Hert, F Turani, S Mathur… - Anesthesia & Analgesia, 2005 - journals.lww.com
Cardiac surgery and some noncardiac procedures are associated with a significant risk of
perioperative cardiac morbid events. Experimental data indicate that clinical concentrations …

Halogenated anaesthetics and cardiac protection in cardiac and non-cardiac anaesthesia

G Landoni, E Bignami, F Oliviero… - Annals of cardiac …, 2009 - journals.lww.com
Volatile anaesthetic agents have direct protective properties against ischemic myocardial
damage. The implementation of these properties during clinical anaesthesia can provide an …