Remodeling of tumor immune microenvironment by oncolytic viruses

B Zhang, X Wang, P Cheng - Frontiers in Oncology, 2021 - frontiersin.org
Oncolytic viruses (OVs) are potential antitumor agents with unique therapeutic mechanisms.
They possess the ability of direct oncolysis and the induction of antitumor immunity. OV can …

[HTML][HTML] Armed oncolytic viruses: A kick-start for anti-tumor immunity

JF De Graaf, L de Vor, RAM Fouchier… - Cytokine & growth factor …, 2018 - Elsevier
Oncolytic viruses (OVs), viruses that specifically result in killing tumor cells, represent a
promising class of cancer therapy. Recently, the focus in the OV therapy field has shifted …

Application of oncolytic virus in tumor therapy

Z Huang, H Guo, L Lin, S Li, Y Yang… - Journal of Medical …, 2023 - Wiley Online Library
Oncolytic viruses (OVs) can selectively kill tumor cells without affecting normal cells, as well
as activate the innate and adaptive immune systems in patients. Thus, they have been …

[HTML][HTML] Oncolytic ImmunoViroTherapy: A long history of crosstalk between viruses and immune system for cancer treatment

S Feola, S Russo, E Ylösmäki, V Cerullo - Pharmacology & therapeutics, 2022 - Elsevier
Cancer Immunotherapy relies on harnessing a patient's immune system to fine-tune specific
anti-tumor responses and ultimately eradicate cancer. Among diverse therapeutic …

Current clinical landscape of oncolytic viruses as novel cancer immunotherapeutic and recent preclinical advancements

CO Yun, JW Hong, AR Yoon - Frontiers in Immunology, 2022 - frontiersin.org
Oncolytic viruses (OVs) have been gaining attention in the pharmaceutical industry as a
novel immunotherapeutic and therapeutic adjuvant due to their ability to induce and boost …

[HTML][HTML] Remodeling the tumor microenvironment by oncolytic viruses: beyond oncolysis of tumor cells for cancer treatment

L Wang, LSC Dunmall, Z Cheng… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Tumor cells manipulate the local environment in which they grow, creating a tumor
microenvironment (TME) that promotes tumor survival and metastasis. The TME is an …

Combination immunotherapy using oncolytic virus for the treatment of advanced solid tumors

CM Oh, HJ Chon, C Kim - International journal of molecular sciences, 2020 - mdpi.com
Oncolytic virus (OV) is a new therapeutic strategy for cancer treatment. OVs can selectively
infect and destroy cancer cells, and therefore act as an in situ cancer vaccine by releasing …

Oncolytic viruses: newest frontier for cancer immunotherapy

MM Rahman, G McFadden - Cancers, 2021 - mdpi.com
Simple Summary Oncolytic viruses (OVs) are viruses that selectively target and kill cancer
cells while sparing normal ones. OVs are from diverse families of viruses, but naturally …

Oncolytic viral therapy and the immune system: a double-edged sword against cancer

G Marelli, A Howells, NR Lemoine, Y Wang - Frontiers in immunology, 2018 - frontiersin.org
Oncolytic viral therapy is a new promising strategy against cancer. Oncolytic viruses (OVs)
can replicate in cancer cells but not in normal cells, leading to lysis of the tumor mass …

Pharmacological modulation of anti-tumor immunity induced by oncolytic viruses

NE Forbes, R Krishnan, JS Diallo - Frontiers in oncology, 2014 - frontiersin.org
Oncolytic viruses (OVs) not only kill cancer cells by direct lysis but also generate a significant
anti-tumor immune response that allows for prolonged cancer control and in some cases …