Subgingival microbiome shifts and community dynamics in periodontal diseases

PI Diaz, A Hoare, BY Hong - Journal of the California Dental …, 2016 - Taylor & Francis
High-throughput 16S rRNA gene sequencing has allowed the characterization of
subgingival microbiome shifts from health to periodontitis identifying health-associated …

Metagenomic sequencing provides new insights into the subgingival bacteriome and aetiopathology of periodontitis

E Ng, JRH Tay, P Balan, MMA Ong… - Journal of …, 2021 - Wiley Online Library
Abstract “Open‐ended” molecular techniques such as 16S rRNA sequencing have revealed
that the oral bacteriome of subgingival plaque is more diverse than originally thought. 16S …

Microbial signatures of health, gingivitis, and periodontitis

L Abusleme, A Hoare, BY Hong, PI Diaz - Periodontology 2000, 2021 - Wiley Online Library
The subgingival crevice harbors diverse microbial communities. Shifts in the composition of
these communities occur with the development of gingivitis and periodontitis, which are …

The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation

L Abusleme, AK Dupuy, N Dutzan, N Silva… - The ISME …, 2013 - academic.oup.com
The goals of this study were to better understand the ecology of oral subgingival
communities in health and periodontitis and elucidate the relationship between inflammation …

Dynamic changes in the subgingival microbiome and their potential for diagnosis and prognosis of periodontitis

B Shi, M Chang, J Martin, M Mitreva, R Lux… - MBio, 2015 - Am Soc Microbiol
The human microbiome influences and reflects the health or disease state of the host.
Periodontitis, a disease affecting about half of American adults, is associated with alterations …

Dysbiosis and alterations in predicted functions of the subgingival microbiome in chronic periodontitis

ME Kirst, EC Li, B Alfant, YY Chi, C Walker… - Applied and …, 2015 - Am Soc Microbiol
Chronic periodontitis is an inflammatory disease of the periodontium affecting nearly 65
million adults in the United States. Changes in subgingival microbiota have long been …

Molecular analysis of the subgingival microbiota in health and disease

RG Ledder, P Gilbert, SA Huws, L Aarons… - Applied and …, 2007 - Am Soc Microbiol
This investigation provides molecular analyses of the periodontal microbiota in health and
disease. Subgingival samples from 47 volunteers with healthy gingivae or clinically …

Understanding the microbial components of periodontal diseases and periodontal treatment-induced microbiological shifts

I Fragkioudakis, MP Riggio… - Journal of Medical …, 2021 - microbiologyresearch.org
In the mid-1960s the microbial aetiology of periodontal diseases was introduced based on
classical experimental gingivitis studies. Since then, numerous studies have addressed the …

Impact of systemic factors in shaping the periodontal microbiome

F Teles, Y Wang, G Hajishengallis… - Periodontology …, 2021 - Wiley Online Library
Since 2010, next‐generation sequencing platforms have laid the foundation to an exciting
phase of discovery in oral microbiology as it relates to oral and systemic health and disease …

Microbiota and metatranscriptome changes accompanying the onset of gingivitis

EM Nowicki, R Shroff, JA Singleton, DE Renaud… - MBio, 2018 - Am Soc Microbiol
Over half of adults experience gingivitis, a mild yet treatable form of periodontal disease
caused by the overgrowth of oral microbes. Left untreated, gingivitis can progress to a more …