Dendritic cells and their role in immunotherapy

A Gardner, Á de Mingo Pulido, B Ruffell - Frontiers in immunology, 2020 - frontiersin.org
Despite significant advances in the field of cancer immunotherapy, the majority of patients
still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have …

Dendritic cells in cancer immunology and immunotherapy

SK Wculek, FJ Cueto, AM Mujal, I Melero… - Nature Reviews …, 2020 - nature.com
Dendritic cells (DCs) are a diverse group of specialized antigen-presenting cells with key
roles in the initiation and regulation of innate and adaptive immune responses. As such …

Immunotherapy with dendritic cells for cancer

A Ballestrero, D Boy, E Moran, G Cirmena… - Advanced drug delivery …, 2008 - Elsevier
Dendritic cells are professional antigen-presenting cells with a key role in both immunity
induction and tolerance maintenance. Dendritic cells are highly specialized in antigen …

Dendritic cells as orchestrators of anticancer immunity and immunotherapy

I Heras-Murillo, I Adán-Barrientos, M Galán… - Nature Reviews …, 2024 - nature.com
Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells
that regulate adaptive immunity, including against cancer. Therefore, understanding the …

The role of dendritic cells in cancer and anti-tumor immunity

AE Marciscano, N Anandasabapathy - Seminars in immunology, 2021 - Elsevier
Dendritic cells (DC) are key sentinels of the host immune response with an important role in
linking innate and adaptive immunity and maintaining tolerance. There is increasing …

The use of dendritic cells in cancer immunotherapy

A Nencioni, F Grünebach, SM Schmidt… - Critical reviews in …, 2008 - Elsevier
Cancer immunotherapy aims at eliciting an immune response directed against tumor
antigens to help fight off residual tumor cells and thereby improve survival and quality of life …

Trial watch: dendritic cell-based anticancer therapy

N Bloy, J Pol, F Aranda, A Eggermont, I Cremer… - …, 2014 - Taylor & Francis
The use of patient-derived dendritic cells (DCs) as a means to elicit therapeutically relevant
immune responses in cancer patients has been extensively investigated throughout the past …

Dendritic cells and cancer immunity

A Gardner, B Ruffell - Trends in immunology, 2016 - cell.com
Dendritic cells (DCs) are central regulators of the adaptive immune response, and as such
are necessary for T-cell-mediated cancer immunity. In particular, antitumoral responses …

Dendritic cells and cancer: from biology to therapeutic intervention

B Wylie, C Macri, JD Mintern, J Waithman - Cancers, 2019 - mdpi.com
Inducing effective anti-tumor immunity has become a major therapeutic strategy against
cancer. Dendritic cells (DC) are a heterogenous population of antigen presenting cells that …

Combination strategies to optimize efficacy of dendritic cell-based immunotherapy

M Van Gulijk, F Dammeijer, JGJV Aerts… - Frontiers in …, 2018 - frontiersin.org
Dendritic cells (DCs) are antigen-presenting cells (APCs) that are essential for the activation
of immune responses. In various malignancies, these immunostimulatory properties are …