Causal effects of serum testosterone levels on brain volume: A sex-stratified Mendelian randomization study

PP Niu, X Wang, YM Xu - Journal of Endocrinological Investigation, 2023 - Springer
Purpose To assess the causal effects of serum testosterone and sex hormone-binding
globulin levels on brain volumetric measurements in women and men. Methods We …

Sex hormones and cognitive function in older men

K Yaffe, LY Lui, J Zmuda… - Journal of the American …, 2002 - Wiley Online Library
OBJECTIVES: Recent studies have suggested that estrogen may improve cognitive function
or prevent cognitive decline in older women. Little research has been conducted on …

Testosterone levels and cognition in elderly men: a review

J Holland, S Bandelow, E Hogervorst - Maturitas, 2011 - Elsevier
Average testosterone levels and many cognitive functions show a decline with age. There is
evidence to suggest that this association is not just age related. Results from cell culture and …

Increasing testosterone levels and effects on cognitive functions in elderly men and women: a review

E Hogervorst, S Bandelow… - Current Drug Targets-CNS …, 2005 - ingentaconnect.com
Low testosterone (T) levels may predispose to Alzheimer disease (AD), but it is unclear
whether this is a comorbid effect due to cachexia, subclinical hyperthyroidism or other co …

A review of the impact of testosterone on brain and aging-related decline in brain behavioural function

AY Onaolapo, OJ Onaolapo - Front Clin Drug Res-CNS Neurolo …, 2022 - books.google.com
The hormone testosterone is known to affect a variety of functions in the body, a number of
which are related to behaviour, and preservation of brain neuronal integrity. Along this line …

Effects of testosterone on cognitive and brain aging in elderly men

SD Moffat - Annals of the New York Academy of Sciences, 2005 - Wiley Online Library
Older age is associated with functional declines throughout the body, including some
aspects of cognitive performance. While dementia develops in only some elderly individuals …

A review on the effects of testosterone supplementation in hypogonadal men with cognitive impairment

NV Mohamad, S Ima-Nirwana, KY Chin - Current drug targets, 2018 - ingentaconnect.com
Cognitive function and testosterone level of men decline concurrently with age. Low
testosterone levels are associated with higher risk of Alzheimer's disease and mild cognitive …

Effects of testosterone therapy on cognitive function in aging: a systematic review

JT Hua, KL Hildreth, VS Pelak - Cognitive and Behavioral …, 2016 - journals.lww.com
Endogenous testosterone in the aging man has been scrutinized extensively in regard to its
effects on performance in many cognitive domains, especially verbal fluency, visuospatial …

Sex hormones and brain volumes in a longitudinal study of middle‐aged men in the CARDIA study

M Elbejjani, PJ Schreiner, DS Siscovick… - Brain and …, 2017 - Wiley Online Library
Introduction Several findings suggest that testosterone (T) is neuroprotective and that
declining T levels during aging are associated with cognitive and brain pathologies; …

[HTML][HTML] Low serum testosterone concentrations are associated with poor cognitive performance in older men but not women

X Dong, H Jiang, S Li, D Zhang - Frontiers in aging neuroscience, 2021 - frontiersin.org
OBJECTIVE: Current evidence on the association between serum testosterone and
cognitive performance has been inconsistent, especially in older adults. To investigate the …