N6-Methyladenosine (m6A) is the most prevalent mRNA modification in mammalian cells
that is mainly catalyzed by the methyltransferase complex of methyltransferase-like 3 and …

RNA methylation is a critical mechanism for regulating the transcription and translation of
specific sequences or for eliminating unnecessary sequences during RNA maturation …

Methyltransferase complex, such as METTL3/METTL14/WTP, catalyze N 6-methyladenosine
(m 6 A), which is the most abundant mRNA modification in mammals. Besides acting as am …

Abstract N 6-methyladenosine (m 6 A) is the most common internal modification of mRNAs
in higher eukaryotic. This process is performed by methyltransferase. Methyltransferase-like …

Abstract N6-methyladenosine (m 6 A) is a prevalent internal RNA modification in higher
eukaryotic cells. As the pivotal m 6 A regulator, RNA methyltransferase-like 3 (METTL3) is …

The methylase METTL3 is the writer enzyme of the N6‐methyladenosine (m6A) modification
of RNA. Using a structure‐based drug discovery approach, we identified a METTL3 inhibitor …

The RNA methyltransferase METTL3 catalyzes N 6-methyladenosine (m6A) modification of
messenger RNAs (mRNAs). It is overexpressed in many types of cancer, including acute …

Abstract Methyltransferase-like 3 (METTL3) was originally known to be responsible for N6-
methyladenosine (m6A) modification of mRNA. Recent studies have found that METTL3 …

Abstract m6A RNA methyltransferase (METTL3‐14) catalyzes the methylation of adenosine
in mRNA and plays important roles in mRNA functions, and it has been implicated in the …

RNA modification plays a crucial role in many biological functions, and its abnormal
regulation is associated with the progression of cancer. Among them, N6-methyladenine …