The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection
A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …
[HTML][HTML] Covid‐19: time for a paradigm change
FM Buonaguro, PA Ascierto, GD Morse… - Reviews in medical …, 2020 - ncbi.nlm.nih.gov
As of May 11, 2020, coronavirus disease 2019 (Covid-19) has been confirmed in 4 152 670
people worldwide, carrying a mortality of approximately 6.8%, 1 compared with a mortality …
people worldwide, carrying a mortality of approximately 6.8%, 1 compared with a mortality …
[HTML][HTML] COVID-19: The emerging immunopathological determinants for recovery or death
Hyperactivation of the host immune system during infection by SARS-CoV-2 is the leading
cause of death in COVID-19 patients. It is also evident that patients who develop …
cause of death in COVID-19 patients. It is also evident that patients who develop …
Innate immunological pathways in COVID-19 pathogenesis
SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …
dysregulation of the innate immune system. This knowledge has emerged from the large …
COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons
The outbreak of the novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)
responsible for coronavirus disease 2019 (COVID-19) has developed into an …
responsible for coronavirus disease 2019 (COVID-19) has developed into an …
In the eye of the COVID-19 cytokine storm
N Vaninov - Nature Reviews Immunology, 2020 - nature.com
Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …
[HTML][HTML] The impact of pre-existing comorbidities and therapeutic interventions on COVID-19
LA Callender, M Curran, SM Bates… - Frontiers in …, 2020 - frontiersin.org
Evidence from the global outbreak of SARS-CoV-2 has clearly demonstrated that individuals
with pre-existing comorbidities are at a much greater risk of dying from COVID-19. This is of …
with pre-existing comorbidities are at a much greater risk of dying from COVID-19. This is of …
[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–current perspectives
JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …
[HTML][HTML] Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration
R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing major threat to global …
respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing major threat to global …
Cytokines and COVID-19: friends or foes?
M Rokni, MR Hamblin, N Rezaei - Human vaccines & …, 2020 - Taylor & Francis
The cytokine storm following sepsis has been proven to be an important mechanism for
triggering acute respiratory distress syndrome, which is a fatal uncontrolled systemic …
triggering acute respiratory distress syndrome, which is a fatal uncontrolled systemic …