Nurture over nature for old antitumor T cells
JE Wilson, JŽ Nikolich - Nature Immunology, 2024 - nature.com
Nurture over nature for old antitumor T cells | Nature Immunology Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …
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The aged tumor microenvironment limits T cell control of cancer
The etiology and effect of age-related immune dysfunction in cancer is not completely
understood. Here we show that limited priming of CD8+ T cells in the aged tumor …
understood. Here we show that limited priming of CD8+ T cells in the aged tumor …
Antitumour T cells stand the test of time
M Reina-Campos, AW Goldrath - 2019 - nature.com
Antitumour T cells stand the test of time Skip to main content Thank you for visiting nature.com.
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Hallmarks of T cell aging
M Mittelbrunn, G Kroemer - Nature immunology, 2021 - nature.com
The aged adaptive immune system is characterized by progressive dysfunction as well as
increased autoimmunity. This decline is responsible for elevated susceptibility to infection …
increased autoimmunity. This decline is responsible for elevated susceptibility to infection …
T cells engineered to target senescence
V Wagner, J Gil - 2020 - nature.com
T cells engineered to target senescence Skip to main content Thank you for visiting nature.com.
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The road not taken en route to T cell exhaustion
B Dash, PG Hogan - Nature Immunology, 2023 - nature.com
The road not taken en route to T cell exhaustion | Nature Immunology Skip to main content
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[HTML][HTML] Senescent Tumor CD8+ T Cells: Mechanisms of Induction and Challenges to Immunotherapy
Simple Summary Immunotherapies harness the hosts' immune system to combat cancer and
are currently used to treat many tumor types. Immunotherapies mainly target T cells, the …
are currently used to treat many tumor types. Immunotherapies mainly target T cells, the …
No intrinsic deficiencies in CD8+ T cell-mediated antitumor immunity with aging
LA Norian, PM Allen - The Journal of Immunology, 2004 - journals.aai.org
Aging is associated with a decline in immune function, particularly within the T cell
compartment. Because CD8+ T cells are critical mediators of protective immunity against …
compartment. Because CD8+ T cells are critical mediators of protective immunity against …
Tumor immunity requires border patrol to fight the enemy within
D Amsen, P Hombrink, RAW van Lier - Nature immunology, 2017 - nature.com
Tumor immunity requires border patrol to fight the enemy within | Nature Immunology Skip
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[HTML][HTML] Rejuvenated T cells attack old tumors
L Galluzzi, E Lugli - Oncoimmunology, 2013 - Taylor & Francis
The adoptive transfer of tumor-specific lymphocytes is actively being tested in the clinic for
the treatment of chronic viral infections and some types of cancer. 1, 2 In the latter setting …
the treatment of chronic viral infections and some types of cancer. 1, 2 In the latter setting …