Aging of human muscle: structure, function and adaptability

MM Porter, AA Vandervoort… - Scandinavian journal of …, 1995 - Wiley Online Library
With increasing age, human skeletal muscles gradually decrease in volume, mainly due to a
reduced number of motor units and muscle fibers, and a reduced size of type 2 fibers. As a …

Ceasing of muscle function with aging: is it the consequence of intrinsic muscle degeneration or a secondary effect of neuronal impairments?

PA Figueiredo, MP Mota, HJ Appell… - European Review of Aging …, 2006 - Springer
Aging is associated with a significant decline in neuromuscular function leading to an
eventual loss of independence and mobility of senescent people. Age-related sarcopenia …

Review on aging, unloading and reloading: changes in skeletal muscle quantity and quality

T Seene, P Kaasik, EM Riso - Archives of gerontology and geriatrics, 2012 - Elsevier
Aging and muscle unloading are associated with a decline in muscle mass, structure, force
and changes in the mechanical properties of skeletal muscle. There is a perception that …

[HTML][HTML] Increase of resting muscle stiffness, a less considered component of age-related skeletal muscle impairment

L Marcucci, C Reggiani - European journal of translational …, 2020 - ncbi.nlm.nih.gov
Elderly people perform more slowly movements of everyday life as rising from a chair,
walking, and climbing stairs. This is in the first place due to the loss of muscle contractile …

[HTML][HTML] The aging neuromuscular system and motor performance

SK Hunter, HM Pereira… - Journal of applied …, 2016 - journals.physiology.org
Age-related changes in the basic functional unit of the neuromuscular system, the motor unit,
and its neural inputs have a profound effect on motor function, especially among the …

Age-associated alterations of the neuromuscular junction

YC Jang, H Van Remmen - Experimental gerontology, 2011 - Elsevier
Age-related loss of muscle mass and function greatly affects quality of life in the elderly
population. Several hypotheses have been proposed but accumulating evidence point to …

Innervation and neuromuscular control in ageing skeletal muscle

RT Hepple, CL Rice - The Journal of physiology, 2016 - Wiley Online Library
Abstract Changes in the neuromuscular system affecting the ageing motor unit manifest
structurally as a reduction in motor unit number secondary to motor neuron loss; fibre type …

Single skeletal muscle fiber mechanical properties: a muscle quality biomarker of human aging

JY Lim, WR Frontera - European Journal of Applied Physiology, 2022 - Springer
Skeletal muscle strength, mass, and function should be carefully monitored for signs of
decline with advanced adult age. An understanding of the pathophysiology and severity of …

Effect of aging on human muscle architecture

MV Narici, CN Maganaris… - Journal of applied …, 2003 - journals.physiology.org
The effect of aging on human gastrocnemius medialis (GM) muscle architecture was
evaluated by comparing morphometric measurements on 14 young (aged 27–42 yr) and on …

Microstructural analysis of skeletal muscle force generation during aging

Y Zhang, JS Chen, Q He, X He… - … journal for numerical …, 2020 - Wiley Online Library
Human aging results in a progressive decline in the active force generation capability of
skeletal muscle. While many factors related to the changes of morphological and structural …