Aging is associated with a decrease in strength in the elderly that can lead to impairment in
performing daily living activities. Weakness with old age can be partially attributed to a well …

According to the World Health Organization, life expectancy at birth has been increasing
steadily in many countries around the world (12). As a consequence, by the year 2025, the …

In both humans and animals there is a progressive loss of muscle strength with age. Tests of
handgrip and knee extension in men show that some decline in strength is evident by the …

With advancing aging, a decline in physical abilities occurs, leading to reduced mobility and
loss of independence. Although many factors contribute to the physio-pathological effects of …

Declining muscle mass and function is one of the main drivers of loss of independence in
the elderly. Sarcopenia is associated with numerous cellular and endocrine perturbations …

Sarcopenia, an age-related condition characterized by progressive skeletal muscle
degeneration, might exist as one of the primary clinical conditions underlying severe …

Overall reductions in muscle strength typically accompany the aging process. However,
older adults show a relatively preserved capacity of producing eccentric strength. The …

As we age, the aerobic and functional capacities of our major physiological systems
progressively decline. In the case of the neuromuscular system, reductions in strength and …

This review aims to provide a summary of current concepts of ageing in relation to the
musculoskeletal system, highlighting recent advances in the understanding of the …

Reduction in muscle strength with aging is due to both loss of muscle mass (quantity) and
intrinsic force production (quality). Along with decreased functional capacity of the muscle …