Profiling chromatin accessibility at the single-cell level provides critical information about cell
type composition and cell-to-cell variation within a complex tissue. Emerging techniques for …

The assay for transposase-accessible chromatin using sequencing (ATAC-seq) provides a
simple and scalable way to detect the unique chromatin landscape associated with a cell …

The assay for transposase-accessible chromatin using sequencing (ATAC-seq) is widely
used to identify regulatory regions throughout the genome. However, very few studies have …

Technical advances have enabled the collection of genome and transcriptome data sets
with single-cell resolution. However, single-cell characterization of the epigenome has …

Background Chromatin accessibility is crucial for gene expression regulation in specific cells
and in multiple biological processes. Assay for Transposase Accessible Chromatin with high …

Chromatin accessibility captures in vivo protein-chromosome binding status, and is
considered an informative proxy for protein-DNA interactions. DNase I and Tn5 transposase …

The advent of single-cell chromatin accessibility profiling has accelerated the ability to map
gene regulatory landscapes but has outpaced the development of scalable software to …

This unit describes Assay for Transposase‐Accessible Chromatin with high‐throughput
sequencing (ATAC‐seq), a method for mapping chromatin accessibility genome‐wide. This …

ATAC-seq is rapidly emerging as one of the major experimental approaches to probe
chromatin accessibility genome-wide. Here, we present 'esATAC', a highly integrated easy …

Abstract The Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) is
a fundamental epigenomics approach and has been widely used in profiling the chromatin …