Glycosaminoglycans in neurodegenerative diseases

W Jin, F Zhang, RJ Linhardt - The Role of Glycosylation in Health and …, 2021 - Springer
Glycosaminoglycans (GAGs) are linear polysaccharides that consist of alternating
disaccharides sequences of uronic acids and/or galactose hexamino sugars most of which …

Glycosaminoglycans

Y Song, F Zhang, RJ Linhardt - The role of glycosylation in health and …, 2021 - Springer
Glycosaminoglycans (GAGs) are important constituents of human glycome. They are
negatively charged unbranched polysaccharides that are usually covalently attached to …

[HTML][HTML] Glycosaminoglycans and glycosaminoglycan mimetics in cancer and inflammation

S Morla - International journal of molecular sciences, 2019 - mdpi.com
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all
mammalian cells and usually covalently attached to proteins, forming proteoglycans. They …

[HTML][HTML] Glycosaminoglycan-protein interactions and their roles in human disease

D Shi, A Sheng, L Chi - Frontiers in molecular biosciences, 2021 - frontiersin.org
Glycosaminoglycans (GAGs) are a family of linear and negatively charged polysaccharides
that exist ubiquitously on the human cell surface as well as in the extracellular matrix. GAGs …

[PDF][PDF] Glycosaminoglycans: from “cellular glue” to novel therapeutical agents

NK Karamanos, GN Tzanakakis - Current opinion in pharmacology, 2012 - academia.edu
Glycosaminoglycans (GAGs), linear macromolecular heteropolysaccharides consisting of
disaccharide repeating units, are classified into several types. Hexuronic acid based GAGs …

Chemistry and function of glycosaminoglycans in the nervous system

NB Schwartz, MS Domowicz - Glycobiology of the Nervous System, 2014 - Springer
The glycosaminoglycan (GAG) family is characterized by covalently linked repeating
disaccharides forming long unbranched polysaccharide chains. Thus far in higher …

Chemistry and function of Glycosaminoglycans in the nervous system

NB Schwartz, MS Domowicz - Glycobiology of the Nervous System, 2022 - Springer
Proteoglycans, and especially their GAG components, participate in numerous biologically
significant interactions with growth factors, chemokines, morphogens, guidance molecules …

Glycosaminoglycan (GAG) biosynthesis and GAG-binding proteins

L Zhang - Progress in molecular biology and translational …, 2010 - Elsevier
Two major types of glycosaminoglycan (GAG) polysaccharides, heparan sulfate and
chondroitin sulfate, are polymerized and modified by enzymes that are encoded by more …

Characterization of structural motifs for interactions between glycosaminoglycans and proteins

J Yang, L Chi - Carbohydrate research, 2017 - Elsevier
Glycosaminoglycans (GAGs) are a family of linear and anionic polysaccharides that play
essential roles in many biological and physiological processes. Interactions between GAGs …

Sulfated non-saccharide glycosaminoglycan mimetics as novel drug discovery platform for various pathologies

DK Afosah, RA Al-Horani - Current medicinal chemistry, 2020 - ingentaconnect.com
Glycosaminoglycans (GAGs) are very complex, natural anionic polysaccharides. They are
polymers of repeating disaccharide units of uronic acid and hexosamine residues. Owing to …