One Cell At a Time (OCAT): a unified framework to integrate and analyze single-cell RNA-seq data

CX Wang, L Zhang, B Wang - Genome biology, 2022 - Springer
Integrative analysis of large-scale single-cell RNA sequencing (scRNA-seq) datasets can
aggregate complementary biological information from different datasets. However, most …

SCDC: bulk gene expression deconvolution by multiple single-cell RNA sequencing references

M Dong, A Thennavan, E Urrutia, Y Li… - Briefings in …, 2021 - academic.oup.com
Recent advances in single-cell RNA sequencing (scRNA-seq) enable characterization of
transcriptomic profiles with single-cell resolution and circumvent averaging artifacts …

Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data

MYY Lee, KH Kaestner, M Li - Genome Biology, 2023 - Springer
Background Single-cell RNA-sequencing (scRNA-seq) measures gene expression in single
cells, while single-nucleus ATAC-sequencing (snATAC-seq) quantifies chromatin …

Independent component analysis based gene co-expression network inference (ICAnet) to decipher functional modules for better single-cell clustering and batch …

W Wang, H Tan, M Sun, Y Han, W Chen… - Nucleic acids …, 2021 - academic.oup.com
With the tremendous increase of publicly available single-cell RNA-sequencing (scRNA-
seq) datasets, bioinformatics methods based on gene co-expression network are becoming …

scCAN: single-cell clustering using autoencoder and network fusion

B Tran, D Tran, H Nguyen, S Ro, T Nguyen - Scientific reports, 2022 - nature.com
Unsupervised clustering of single-cell RNA sequencing data (scRNA-seq) is important
because it allows us to identify putative cell types. However, the large number of cells (up to …

scMerge: Integration of multiple single-cell transcriptomics datasets leveraging stable expression and pseudo-replication

Y Lin, S Ghazanfar, K Wang, JA Gagnon-Bartsch… - bioRxiv, 2018 - biorxiv.org
Concerted examination of multiple collections of single cell RNA-Seq (scRNA-Seq) data
promises further biological insights that cannot be uncovered with individual datasets …

scMerge leverages factor analysis, stable expression, and pseudoreplication to merge multiple single-cell RNA-seq datasets

Y Lin, S Ghazanfar, KYX Wang… - Proceedings of the …, 2019 - National Acad Sciences
Concerted examination of multiple collections of single-cell RNA sequencing (RNA-seq)
data promises further biological insights that cannot be uncovered with individual datasets …

Assessing transcriptomic heterogeneity of single-cell RNASeq data by bulk-level gene expression data

KL Tiong, D Luzhbin, CH Yeang - BMC bioinformatics, 2024 - Springer
Background Single-cell RNA sequencing (sc-RNASeq) data illuminate transcriptomic
heterogeneity but also possess a high level of noise, abundant missing entries and …

scID uses discriminant analysis to identify transcriptionally equivalent cell types across single-cell RNA-seq data with batch effect

K Boufea, S Seth, NN Batada - IScience, 2020 - cell.com
The power of single-cell RNA sequencing (scRNA-seq) stems from its ability to uncover cell
type-dependent phenotypes, which rests on the accuracy of cell type identification. However …

scID: identification of transcriptionally equivalent cell populations across single cell RNA-seq data using discriminant analysis

K Boufea, S Seth, NN Batada - BioRxiv, 2018 - biorxiv.org
The power of single cell RNA sequencing (scRNA-seq) stems from its ability to uncover cell
type-dependent phenotypes, which rests on the accuracy of cell type identification. However …