Background and aims: The genotypic method could significantly shorten the time needed to
obtain antibiotic susceptibility data for Helicobacter pylori. The aim of this study was to …

Failure to eradicate Helicobacter pylori infection is often a result of antimicrobial resistance,
which for clarithromycin is typically mediated by specific point mutations in the 23S rRNA …

Mixed infections and heteroresistance of Helicobacter pylori contribute to decreased efficacy
of treatments. This study aimed to investigate frequency of clarithromycin heteroresistance …

Conventional triple therapies for Helicobacter pylori (H. pylori) eradication have recently
shown a disappointing reduction in effectiveness in many countries. The main reason for …

Background: Helicobacter pylori is a pathogenic bacterium that infects a half of the human
population. In Chile, between 55% and 79% of people are colonized by H. pylori. At present …

The aim of this study was to evaluate the secondary resistance in Helicobacter pylori (Hp)
infected patients who had failed a first-line therapy, and to compare the genotypic tests …

Abstract Background The effectiveness of Helicobacter pylori first-line treatment has
decreased drastically with the rise of strains resistant to clarithromycin. Therapy failure has …

Resistance to clarithromycin, a macrolide antibiotic used in the first-line treatment of
Helicobacter pylori infection, is the most important cause of treatment failure. Although most …

The accuracy of genotypic resistance to levofloxacin (gyrA mutations) and its agreement with
treatment outcomes after levofloxacin-based therapy have not been reported. We aimed to …

AIM: To characterize the types of mutations present in the 23S rRNA genes of Malaysian
isolates of clarithromycin-resistant Helicobacter pylori (H pylori). METHODS: Clarithromycin …