Evaluation of a New Test, GenoType HelicoDR, for Molecular Detection of Antibiotic Resistance in Helicobacter pylori

E Cambau, V Allerheiligen, C Coulon… - Journal of Clinical …, 2009 - Am Soc Microbiol
The eradication rate of Helicobacter pylori by standard therapy is decreasing due to
antibiotic resistance, mainly to clarithromycin. Our aim was to provide a new molecular test …

High rate of A2142G point mutation associated with clarithromycin resistance among Iranian Helicobacter pylori clinical isolates

R Khashei, M Dara, A Bazargani, K Bagheri Lankarani… - Apmis, 2016 - Wiley Online Library
This study aimed to investigate the clarithromycin resistance and its associated molecular
mechanisms among Helicobacter pylori isolates from dyspeptic patients in Shiraz, Iran. From …

A novel stool PCR test for Helicobacter pylori may predict clarithromycin resistance and eradication of infection at a high rate

E Beckman, I Saracino, G Fiorini, C Clark… - Journal of clinical …, 2017 - Am Soc Microbiol
Clarithromycin-based regimens are commonly used as a first-line therapy for Helicobacter
pylori-positive patients; however, resistance to clarithromycin has led to treatment failures …

[HTML][HTML] Helicobacter pylori 23S rRNA gene A2142G, A2143G, T2182C, and C2195T mutations associated with clarithromycin resistance detected in Sudanese …

AM Albasha, MM Elnosh, EH Osman, DM Zeinalabdin… - BMC microbiology, 2021 - Springer
Abstract Background Clarithromycin resistant Helicobacter pylori (H. pylori) strains represent
a worldwide health problem. These stains are usually carrying mutations within the 23S …

[HTML][HTML] Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA …

J Chen, L Ye, L Jin, X Xu, P Xu, X Wang… - Annals of Clinical …, 2018 - Springer
Background Clarithromycin (CLR) resistance has become a predominant factor for treatment
failure of Helicobacter pylori eradication. Although the molecular mechanism of CLR …

[HTML][HTML] High frequency of A2143G mutation in clarithromycin-resistant Helicobacter pylori isolates recovered from dyspeptic patients in Iran

AT Abadi, T Taghvaei, A Ghasemzadeh… - Saudi Journal of …, 2011 - journals.lww.com
Materials and Methods: A total of 147 consecutive patients infected with H. pylori were
included for determining the status of resistant H. pylori strains. With upper gastroscopy …

[PDF][PDF] Clarithromycin resistance and 23S rRNA mutations in Helicobacter pylori isolates in Iran

M Kargar, M Baghernejad, A Doosti… - Afr J Microbiol …, 2011 - academicjournals.org
To determine the 23S rRNA point mutations in clarithromycin resistance of Helicobacter
pylori strains isolated from southwest, Iran. This was a cross-sectional survey, which was …

[HTML][HTML] The study of mutation in 23S rRNA resistance gene of Helicobacter pylori to clarithromycin in patients with gastrointestinal disorders in Isfahan—Iran

F Khademi, J Faghri, S Moghim… - Advanced biomedical …, 2014 - journals.lww.com
Background: Helicobacter pylori antimicrobial resistance is an important factor responsible
for treatment failure. The purpose of this study was evaluating the prevalence of point …

[HTML][HTML] Polymorphism of virulence genes and biofilm associated with in vitro induced resistance to clarithromycin in Helicobacter pylori

NA Rosli, AR Al-Maleki, MF Loke, EG Chua, MA Alhoot… - Gut Pathogens, 2023 - Springer
Background Clarithromycin-containing triple therapy is commonly used to treat Helicobacter
pylori infections. Clarithromycin resistance is the leading cause of H. pylori treatment failure …

Antimicrobial resistance rate of Helicobacter pylori isolates and detection of mechanism of clarithromycin resistance

SJ KIM, JG KIM, K Jung, YH HONG… - Korean Journal of …, 2001 - pesquisa.bvsalud.org
BACKGROUND: Antimicrobial resistance is considered as the primary reason for
eradication failure of Helicobacter pylori. Resistance to clarithromycin is mostly due to the …