Detection of four clarithromycin resistance point mutations in Helicobacter pylori: comparison of real-time PCR and PCR-RFLP methods

M Kargar, A Doosti, S Ghorbani-Dalini - Comparative Clinical Pathology, 2013 - Springer
Helicobacter pylori infection can be eradicated in up to 90% of patients using current
combination of triple therapies, of which clarithromycin is a key component. The …

Prevalence OFA2143G AND A2144G point mutations responsible for clarithromycin resistance among Helicobacter pylori strains in Bushehr, IRAN

S Tajbakhsh, J Falahi, N Motamed, SM Tabib… - 2016 - sid.ir
Background: Resistance to clarithromycin in HELICOBACTER PYLORI has become one of
the most important reasons for failure of antibiotic eradication therapies. This resistance is …

Application of 3′-mismatched reverse primer PCR compared with real-time PCR and PCR-RFLP for the rapid detection of 23S rDNA mutations associated with …

NC Elviss, AJ Lawson, RJ Owen - International journal of antimicrobial …, 2004 - Elsevier
Helicobacter pylori clarithromycin (Cla) resistance dramatically reduces efficacy of
eradication therapy. In this study, 3′-mismatched reverse primer PCR (3M-PCR), real-time …

Influence of a 23S ribosomal RNA mutation in Helicobacter pylori strains on the in vitro synergistic effect of clarithromycin and amoxicillin

T Sakinc, B Baars, N Wüppenhorst, M Kist… - BMC research …, 2012 - Springer
Background Clarithromycin (CLR) is the most commonly recommended antibiotic in
Helicobacter pylori eradication regimens, but the prevalence of CLR-resistant H. pylori is …

Pyrosequencing analysis for rapid and accurate detection of clarithromycin resistance-associated mutations in Iranian Helicobacter pylori isolates

H Alavifard, A Nabavi-Rad, K Baghaei, A Sadeghi… - BMC Research …, 2023 - Springer
Abstract Background Treatment of Helicobacter pylori (H. pylori) infection has become
challenging following the development of primary antibiotic resistance. A primary therapeutic …

Oligonucleotide microarray: A new rapid method for screening the 23S rRNA gene of Helicobacter pylori for single nucleotide polymorphisms associated with …

S Chen, Y Li, C Yu - Journal of gastroenterology and …, 2008 - Wiley Online Library
Abstract Background and Aim: Resistance to antibiotics in Helicobacter pylori is increasing
and becoming a serious problem in eradication treatment. Resistance of H. pylori to …

Clarithromycin Resistance Mutations in Helicobacter pylori in Association with Virulence Factors and Antibiotic Susceptibility of the Strains

L Boyanova, R Markovska, D Yordanov… - Microbial Drug …, 2016 - liebertpub.com
Antibiotic resistance is the major cause for Helicobacter pylori eradication failure. H. pylori
clarithromycin resistance mutations were evaluated in 84 (82 phenotypically clarithromycin …

Helicobacter pylori Eradication According to Sequencing-Based 23S Ribosomal RNA Point Mutation Associated with Clarithromycin Resistance

SI Seo, BJ Do, JG Kang, HS Kim, MK Jang… - Journal of Clinical …, 2019 - mdpi.com
Background/Aims: Clarithromycin resistance in Helicobacter pylori is associated with point
mutations in the 23S ribosomal RNA (rRNA) gene. We investigated the point mutations in …

Molecular Assessment of Resistance to Clarithromycin in Helicobacter pylori Strains Isolated from Patients with Dyspepsia by Fluorescent In Situ Hybridization in the …

J Vazirzadeh, J Falahi, S Moghim… - BioMed Research …, 2020 - Wiley Online Library
Background and Aims. Helicobacter pylori is a common infectious bacterium mostly found in
gastroduodenal diseases. The increased prevalence of clarithromycin‐resistant H. pylori …

Determination of single nucleotide mutations in the 23S rRNA gene of Helicobacter pylori related to clarithromycin resistance in a population from Cauca, Colombia

CP Acosta, FA Hurtado, AA Trespalacios - Biomédica, 2014 - scielo.org.co
Abstract ACOSTA, Claudia Patricia; HURTADO, Fabián Andrés and TRESPALACIOS, Alba
Alicia. Determination of single nucleotide mutations in the 23S rRNA gene of Helicobacter …