Resistance of Helicobacter pylori to clarithromycin occurs with a prevalence ranging from 0
to 15%. This has an important clinical impact on dual and triple therapies, in which …

Background. The occurrence of clarithromycin resistance among Helicobacter pylori strains
is a major cause of the treatment failure. Resistance to this drug is conferred by point …

We have developed a rapid PCR-oligonucleotide ligation assay that can discriminate single
base substitutions that are associated with clarithromycin resistance in Helicobacter pylori …

A large survey of antimicrobial resistance of Helicobacter pylori was performed in France in
2014: 984 patients were enrolled by 75 gastroenterologists all over the country. Among the …

Background The high prevalence of clarithromycin-resistant strains of Helicobacter pylori is
a main challenge for the successful treatment of gastrointestinal infections. Point mutations …

Background Antimicrobial resistance of H. pylori can lead to treatment failure. Importantly,
several studies have reported on heteroresistance, ie the presence of resistant and …

Clarithromycin is recognised as the key antibiotic for Helicobacter pylori treatment, since it
has the most powerful bactericidal effect in vitro compared to other available molecules …

Background Antimicrobial therapy is recommended to eradicate Helicobacter (H.) pylori in
infected individuals. As first‐line treatments are empiric, knowledge of antimicrobial …

Background. This study analyzes clarithromycin resistance status and 23S rRNA gene
mutations in Helicobacter pylori strains from Central Italian patients. Materials and methods …

Methods Gastric biopsies were obtained by endoscopy from patients with gastric symptoms.
H. pylori was cultured according to standard microbiological procedures and clarithromycin …