[HTML][HTML] Dehydroepiandrosterone sulfate level varies nonlinearly with symptom severity in major depressive disorder

D Uh, HG Jeong, KY Choi, SY Oh, S Lee… - Clinical …, 2017 - ncbi.nlm.nih.gov
Objective The pathophysiology of major depressive disorder (MDD) is still not well
understood. Conflicting results for surrogate biomarkers in MDD have been reported, which …

Plasma dehydroepiandrosterone sulfate levels in patients with major depressive disorder correlate with remission during treatment with antidepressants

T Morita, K Senzaki, R Ishihara… - Human …, 2014 - Wiley Online Library
Objective We attempted to investigate whether dehydroepiandrosterone sulfate (DHEA‐S)
levels are associated with remission of major depressive disorder by assessing scores on …

Clinical significance of decreased protein expression of dehydroepiandrosterone sulfate in the development of depression: a meta-analysis

Q Hu, SY Zhang, F Liu, YL Zhang, DM Zhu… - Journal of affective …, 2015 - Elsevier
Background Previous evidence has shown that adrenal androgens,
dehydroepiandrosterone (DHEA) and its sulfate derivative (DHEAS) have significant …

Venlafaxine and mirtazapine treatment lowers serum concentrations of dehydroepiandrosterone-sulfate in depressed patients remitting during the course of treatment

G Paslakis, P Luppa, M Gilles, D Kopf… - Journal of psychiatric …, 2010 - Elsevier
OBJECTIVES: The adrenal androgen dehydroepiandrosterone-sulfate (DHEA-S) seems to
be involved in the pathophysiology of depression, although its precise role in the etiology …

[HTML][HTML] Higher serum dehydroepiandrosterone sulfate protects against the onset of depression in the elderly: findings from the English Longitudinal Study of Aging …

LH Souza-Teodoro, C de Oliveira, K Walters… - …, 2016 - Elsevier
Depression is one of the major causes of disability worldwide, but the complete etiology of
depression is not fully understood. Dehydroepiandrosterone (DHEA) and its sulphated form …

Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression

CM Hough, D Lindqvist, ES Epel, MS Denis… - …, 2017 - Elsevier
Background Dehydroepiandrosterone (DHEA) and its sulfated ester DHEA-sulfate (DHEA-
S),(together DHEA [S]), are the most abundant adrenal steroids in humans and are found in …

DHEAS and cortisol/DHEAS-ratio in recurrent depression: state, or trait predicting 10-year recurrence?

RJT Mocking, CM Pellikaan, A Lok, J Assies… - …, 2015 - Elsevier
Background Major depressive disorder (MDD) has been associated with low
dehydroepiandrosterone-sulphate (DHEAS),–particularly relative to high cortisol–although …

Higher serum dehydroepiandrosterone sulfate levels are protectively associated with depressive symptoms in men, but not in women: a community-based cohort …

T Michikawa, Y Nishiwaki, M Nakano… - The American Journal of …, 2013 - Elsevier
Objective Dehydroepiandrosterone sulfate (DHEAS) appears to have a protective effect
against depression, but evidence from prospective cohort studies is sparse. Therefore, we …

Morning salivary dehydroepiandrosterone (DHEA) qualifies as the only neuroendocrine biomarker separating depressed patients with and without prior history of …

A Agorastos, A Heinig, A Sommer… - Journal of Psychiatric …, 2023 - Elsevier
Background Hypothalamic-pituitary-adrenal (HPA) axis abnormalities in major depression
(MDD) have been consistently reported in psychiatry and extend to several neurosteroids …

Difference in pre-and post-treatment plasma DHEA levels were significantly and positively correlated with difference in pre-and post-treatment Hamilton depression …

CC Hsiao - Psychoneuroendocrinology, 2006 - Elsevier
OBJECTIVE: Clinical studies of endogenous concentrations of dehydroepiandrosterone
(DHEA) and its relation to depression are limited. This study examined whether pre-and post …