Cancer is a leading cause of death worldwide and around 10 million deaths in 2020 were
related to cancer. There are a number of therapeutic modalities for cancer such as …

SOX2 is a transcription factor involved in multiple stages of embryonic development. In
related reports, SOX2 was found to be abnormally expressed in tumor tissues and correlated …

SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and
contains a high-mobility group (HMG) domain, which permits highly specific DNA binding …

Introduction: SOX2 is a transcription factor that is important in the development and
maintenance of the stem cell state. Furthermore, SOX2 is associated with cancer …

The transcription factor Sox2 plays an important role in various phases of embryonic
development, including cell fate and differentiation. These key regulatory functions are …

Objective The aim of the this study was to analyze the status of sex-determining region Y-
related high-mobility group box 4 (SOX4) expression in varied human cancers and its …

The transcription factor SOX2 is essential for embryonic development and plays a crucial
role in maintaining the stemness of embryonic cells and various adult stem cell populations …

Introduction: SOX2 plays a crucial role in tumor development, cancer stem cell maintenance,
and cancer progression. Mechanisms of SOX2 gene regulation in human breast and …

Sex-determining region Y-related high mobility group box 4 (SOX4) has been proven to
serve as a critical role in cancer development and progression. However, little is known …

SOX2 is a well-characterized pluripotent factor that is essential for stem cell self-renewal,
reprogramming, and homeostasis. The cellular levels of SOX2 are precisely regulated by a …