Current pharmacological treatments for SARS-COV-2: A narrative review

G Nittari, G Pallotta, F Amenta, SK Tayebati - European Journal of …, 2020 - Elsevier
The novel coronavirus, later identified as SARS-CoV-2, originating from Wuhan in China in
November 2019, quickly spread around the world becoming a pandemic. Despite the …

[HTML][HTML] Treatment options for COVID-19: The reality and challenges

SS Jean, PI Lee, PR Hsueh - Journal of microbiology, immunology and …, 2020 - Elsevier
An outbreak related to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
was first reported in Wuhan, China in December 2019. An extremely high potential for …

Efficacy and safety of Molnupiravir in COVID-19 patients: A systematic review

KR Mali, M Eerike, GM Raj, D Bisoi… - Irish Journal of Medical …, 2023 - Springer
Background Molnupiravir is an oral antiviral drug that received Emergency Use
Authorization in three countries for the treatment of mild COVID-19. The aim of this …

SARS-CoV-2: recent reports on antiviral therapies based on lopinavir/ritonavir, darunavir/umifenovir, hydroxychloroquine, remdesivir, favipiravir and other drugs for …

M Costanzo, MAR De Giglio… - Current medicinal …, 2020 - ingentaconnect.com
Here we report on the most recent updates on experimental drugs successfully employed in
the treatment of the disease caused by SARS-CoV-2 coronavirus, also referred to as COVID …

A proof-of-concept study on the genomic evolution of Sars-Cov-2 in molnupiravir-treated, paxlovid-treated and drug-naïve patients

C Alteri, V Fox, R Scutari, GJ Burastero, S Volpi… - Communications …, 2022 - nature.com
Little is known about SARS-CoV-2 evolution under Molnupiravir and Paxlovid, the only
antivirals approved for COVID-19 treatment. By investigating SARS-CoV-2 variability in 8 …

COVID-19 impacts, diagnosis and possible therapeutic techniques: a comprehensive review

A Aziz, M Asif, G Ashraf, Q Yang… - Current Pharmaceutical …, 2021 - ingentaconnect.com
Background: The spread of COVID-19 has become a growing cause of mortalities over the
globe since its major outbreak in December 2019. The scientific and medical communities …

Directly acting antivirals for COVID-19: where do we stand?

SL Teoh, YH Lim, NM Lai, SWH Lee - Frontiers in microbiology, 2020 - frontiersin.org
The outbreak of a novel coronavirus (SARS-CoV-2) in Wuhan, China in December 2019 has
now become a pandemic with no approved therapeutic agent. At the moment, the genomic …

Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19: a meta-analysis

W Wen, C Chen, J Tang, C Wang, M Zhou… - Annals of …, 2022 - Taylor & Francis
Background The coronavirus disease (COVID-19) epidemic has not been completely
controlled. Although great achievements have been made in COVID-19 research and many …

Recent progress and challenges in drug development against COVID-19 coronavirus (SARS-CoV-2)-an update on the status

TM Abd El-Aziz, JD Stockand - Infection, Genetics and evolution, 2020 - Elsevier
Coronaviruses are a large group of viruses known to cause illnesses that vary between the
common cold and more severe diseases to include severe acute respiratory syndrome …

[HTML][HTML] Current status of oral antiviral drug treatments for SARS-CoV-2 infection in non-hospitalized patients

DV Parums - … science monitor: international medical journal of …, 2022 - ncbi.nlm.nih.gov
On 4 th November 2021, the first oral antiviral drug for COVID-19, molnupiravir (Lagevrio®),
received full regulatory approval from the Medicines and Healthcare Products Regulatory …