After peripheral nerve damage macrophages infiltrate the dorsal root ganglia (DRG) in
which cell bodies of lesioned neurons are located. However, infiltration of macrophages into …

Objective In arthritis, macrophages invade the affected joint. Experimental arthritis models
have shown that macrophages also invade the dorsal root ganglia (DRGs) of the inflamed …

Pain is the major debilitating symptom of osteoarthritis (OA), which is difficult to treat. In OA
patients joint tissue damage only poorly associates with pain, indicating other mechanisms …

Objective The expression of proinflammatory factors such as tumor necrosis factor α (TNFα),
interleukin‐6 (IL‐6), IL‐8, and prostaglandin E2 (PGE2) is significantly correlated with the …

After partial ligation of mouse sciatic nerve, the subtypes of macrophages were examined in
the injured nerve and dorsal root ganglia (DRGs). Many M1 macrophages, which were …

The proinflammatory cytokines tumor necrosis factor‐α (TNF‐α) and interleukin‐6 (IL‐6) not
only promote and maintain inflammation, they also contribute to the generation and …

The distribution of major histocompatibility complex class II (MHC II)-positive non-neuronal
cells and T-lymphocytes was examined immunohistochemically in dorsal root ganglia …

The mechanisms underlying rheumatoid arthritis (RA)‐induced pain are still not fully
elucidated, and accumulating data indicate that peripheral inflammation is not the only factor …

Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant
expansion and proliferation of macrophages around injured sensory neurons in dorsal root …

Increases in the levels of proinflammatory cytokines, such as TNFα, have been intricately
linked with arthritis and the pathogenesis of several models of neuropathic pain. In addition …