Cytomegalovirus (CMV) is a highly species-specific virus that has co-evolved with its host
over millions of years and thus restricting cross-species infection. To examine the extent to …

Cynomolgus macaques have been widely used as an animal model in preclinical
biomedical research and are becoming more popular among HIV/SIV vaccine researchers …

Highlights•Nonhuman primate (NHP) CMVs are most closely related to human CMV
(HCMV).•Rhesus CMV (RhCMV) bears numerous genomic and functional similarities to …

Rhesus cytomegalovirus (RhCMV) infection of rhesus macaques (Macaca mulatta) is a
valuable nonhuman primate model of human CMV (HCMV) persistence and pathogenesis …

Cytomegaloviruses (CMV) are highly species-specific due to millennia of co-evolution and
adaptation to their host, with no successful experimental cross-species infection in primates …

Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict
species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal …

Human cytomegalovirus (HCMV), a member of an ancient family of viruses (Herpesviridae),
has acquired the capacity to maintain a lifelong persistent infection within an …

Cytomegalovirus (CMV) infection is the most common opportunistic infection in
immunosuppressed individuals, such as transplant recipients or people living with HIV/AIDS …

Human cytomegalovirus (HCMV) possesses low pathogenic potential in an
immunocompetent host. In the immunosuppressed host, however, a wide spectrum of …

Background Cytomegaloviruses belong to a large, ancient, genus of DNA viruses comprised
of a wide array of species-specific strains that occur in diverse array of hosts. Methods In this …