Co-expression of hepatitis C virus polytope–HBsAg and p19-silencing suppressor protein in tobacco leaves
S Mohammadzadeh, F Roohvand… - Pharmaceutical …, 2016 - Taylor & Francis
Context: Plants transformed by virus-based vectors have emerged as promising tools to
rapidly express large amounts and inexpensive antigens in transient condition. Objective …
rapidly express large amounts and inexpensive antigens in transient condition. Objective …
[HTML][HTML] Enhanced-transient expression of hepatitis C virus core protein in Nicotiana tabacum, a protein with potential clinical applications
S Mohammadzadeh, A Khabiri, F Roohvand… - Hepatitis …, 2014 - ncbi.nlm.nih.gov
Background: Hepatitis C virus (HCV) is major cause of liver cirrhosis in humans. HCV capsid
(core) protein (HCVcp) is a highly demanded antigen for various diagnostic, immunization …
(core) protein (HCVcp) is a highly demanded antigen for various diagnostic, immunization …
Expression of chimeric HCV peptide in transgenic tobacco plants infected with recombinant alfalfa mosaic virus for development of a plant-derived vaccine against …
AK El Attar, AM Shamloul, AA Shalaby, BY Riad… - African Journal of …, 2004 - ajol.info
Hepatitis C virus (HCV) is the major etiologic agent of blood transfusion–associated and
sporadic non-A non-B hepatitis affecting more than 180 million worldwide. Vaccine …
sporadic non-A non-B hepatitis affecting more than 180 million worldwide. Vaccine …
Hepatitis C virus E2 envelope glycoprotein produced in Nicotiana benthamiana triggers humoral response with virus‐neutralizing activity in vaccinated mice
MO Dobrica, A van Eerde, C Tucureanu… - Plant biotechnology …, 2021 - Wiley Online Library
Chronic infection with hepatitis C virus (HCV) remains a leading cause of liver‐related
pathologies and a global health problem, currently affecting more than 71 million people …
pathologies and a global health problem, currently affecting more than 71 million people …
Plant-based vaccines: novel and low-cost possible route for Mediterranean innovative vaccination strategies
A plant bioreactor has enormous capability as a system that supports many biological
activities, that is, production of plant bodies, virus-like particles (VLPs), and vaccines …
activities, that is, production of plant bodies, virus-like particles (VLPs), and vaccines …
[HTML][HTML] Heterologous Expression of Hepatitis C Virus Core Protein in Oil Seeds of Brassica napus L.
S Mohammadzadeh, F Roohvand… - Jundishapur Journal …, 2015 - ncbi.nlm.nih.gov
Background: Hepatitis c virus (HCV), prevalent among 3% of the world population, is a major
worldwide public health concern and an effective vaccination could help to overcome this …
worldwide public health concern and an effective vaccination could help to overcome this …
Immunogenic properties of a chimeric plant virus expressing a hepatitis C virus (HCV)-derived epitope: new prospects for an HCV vaccine
G Piazzolla, M Nuzzaci, C Tortorella, E Panella… - Journal of clinical …, 2005 - Springer
A vaccine against Hepatitis C virus (HCV) is urgently needed due to the unsatisfactory
clinical response to current therapies. We evaluated the immunological properties of a …
clinical response to current therapies. We evaluated the immunological properties of a …
Expression of an HCV Core Antigen Coding Gene in Tobacco (N. tabacum L.)
I Nianiou, K Kalantidis, P Madesis… - Preparative …, 2008 - Taylor & Francis
Hepatitis C virus (HCV) is the major agent causing chronic liver disease. The core gene is
the most conserved sequence in the HCV genome and proved immunoreactive when …
the most conserved sequence in the HCV genome and proved immunoreactive when …
Lettuce‐produced hepatitis C virus E1E2 heterodimer triggers immune responses in mice and antibody production after oral vaccination
JL Clarke, L Paruch, MO Dobrica… - Plant biotechnology …, 2017 - Wiley Online Library
The hepatitis C virus (HCV) is a major etiologic agent for severe liver diseases (eg cirrhosis,
fibrosis and hepatocellular carcinoma). Approximately 140 million people have chronic HCV …
fibrosis and hepatocellular carcinoma). Approximately 140 million people have chronic HCV …
Immunogenic properties of chimeric potato virus X particles displaying the hepatitis C virus hypervariable region I peptide R9
K Uhde-Holzem, V Schlösser, S Viazov… - Journal of virological …, 2010 - Elsevier
The immunogenic properties of chimeric potato virus X (PVX) particles engineered to display
the synthetic R9 peptide have been evaluated. The R9 peptide is a consensus sequence …
the synthetic R9 peptide have been evaluated. The R9 peptide is a consensus sequence …