Metformin has been studied for its anticancer effects by regulating T cell functions. However,
the mechanisms through which metformin stimulates the differentiation of memory T cells …

Type 2 diabetes is a major health problem associated with excess mortality and morbidity.
Vascular complications are one of the most serious consequences of this disorder …

Metformin has been extensively used for the treatment of type 2 diabetes, and it may also
promote healthy aging. Despite its widespread use and versatility, metformin's mechanisms …

Metformin, one of the most commonly used drugs for the treatment of type II diabetes, was
recently found to exert its therapeutic effects, at least in part, by activating the AMP-activated …

Diabetes is usually associated with inflammation. Inflammation contributes to the
development of diabetes. Traditional Chinese medicines (TCM) play an important role in …

Fibrosis is a physiological response to organ injury and is characterized by the excessive
deposition of connective tissue components in an organ, which results in the disruption of …

In Legionella pneumophila infection, macrophages play a critical role in the host defense
response. Metformin, an oral drug for type 2 diabetes, is attracting attention as a new …

Background Despite their revolutionary success in cancer treatment over the last decades,
immunotherapies encounter limitations in certain tumor types and patients. The efficacy of …

Metformin is the first-line medication for treatment of type 2 diabetes and has been shown to
reduce heart damage and death. However, mechanisms by which metformin protects human …

The biguanide metformin has been used as first-line therapy in type 2 diabetes mellitus
(T2DM) treatment for several decades. In addition to its glucose-lowering properties and its …