Rationale: In life-threatening coronavirus disease (COVID-19), corticosteroids reduce
mortality, suggesting that immune responses have a causal role in death. Whether this …

The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), continues to spread globally despite the worldwide …

The clinical spectrum of COVID-19 varies and the differences in host response
characterizing this variation have not been fully elucidated. COVID-19 disease severity …

Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …

Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying
COVID-19. We examine cellular, humoral and cytokine responses covering 382 immune …

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of
coronavirus disease 2019 (COVID-19), has resulted in a pandemic that has had widespread …

Abstract COVID-19 is associated with 5.1% mortality. Although the virological,
epidemiological, clinical, and management outcome features of COVID-19 patients have …

SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

Immune profiling of COVID-19 patients has identified numerous alterations in both innate
and adaptive immunity. However, whether those changes are specific to SARS-CoV-2 or …