[HTML][HTML] Managing potential drug interactions of Nirmatrelvir/Ritonavir in COVID‐19 patients: a perspective from an Israeli Cross‐Sector Collaboration

S Guy‐Alfandary, S Zhurat, M Berlin… - Clinical …, 2022 - ncbi.nlm.nih.gov
In this perspective, we highlight major clinical pharmacologyrelated issues encountered
since the rapid introduction of nirmatrelvir/ritonavir in Israel. We describe the rationale for the …

Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a …

M Zeitlinger, BCP Koch, R Bruggemann… - Clinical …, 2020 - Springer
There is an urgent need to identify optimal antiviral therapies for COVID-19 caused by SARS-
CoV-2. We have conducted a rapid and comprehensive review of relevant pharmacological …

Use of antivirals in SARS-CoV-2 infection. Critical review of the role of remdesivir

S Moreno, B Alcázar, C Dueñas… - Drug Design …, 2022 - Taylor & Francis
The aim of this report is to review the literature and shed light on the uncertainties
surrounding the use of antiviral agents in general and remdesivir in COVID-19 patients. This …

Molnupiravir for the treatment of non-severe COVID-19: a systematic review and meta-analysis of 14 randomized trials with 34 570 patients–authors' response

M Sun, H Lai, Z Zhang, L Ge - Journal of Antimicrobial …, 2023 - academic.oup.com
We thank Drs Kow, Ramachandram and Hasan for their interest in our review and their
knowledgeable comments. 1 We agree with your thoughtful view that the most important …

Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trials

A Izcovich, RA Siemieniuk, JJ Bartoszko, L Ge… - BMJ open, 2022 - bmjopen.bmj.com
Background To summarise specific adverse effects of remdesivir, hydroxychloroquine and
lopinavir/ritonavir in patients with COVID-19. Methods We searched 32 databases through …

Le nirmatrelvir-ritonavir (Paxlovid®), un traitement contre la Covid-19

J Buxeraud, S Faure, É Fougere - Actualités pharmaceutiques, 2022 - Elsevier
Nirmatrelvir-ritonavir (Paxlovid®), a treatment for Covid-19 The nirmatrelvir-ritonavir
(Paxlovid®) is a treatment against Covid-19 available in pharmacies since February 4, 2022 …

Evaluation of the efficacy and safety of intravenous remdesivir in adult patients with severe COVID-19: study protocol for a phase 3 randomized, double-blind, placebo …

Y Wang, F Zhou, D Zhang, J Zhao, R Du, Y Hu… - Trials, 2020 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19), caused by a novel corinavirus
(later named SARS-CoV-2 virus), was fistly reported in Wuhan, Hubei Province, China …

A review of the preclinical and clinical efficacy of remdesivir, hydroxychloroquine, and lopinavir-ritonavir treatments against COVID-19

D Maciorowski, SZE Idrissi, Y Gupta… - … the Science of Drug …, 2020 - journals.sagepub.com
In December of 2019, an outbreak of a novel coronavirus flared in Wuhan, the capital city of
the Hubei Province, China. The pathogen has been identified as a novel enveloped RNA …

[HTML][HTML] Effectiveness and adverse events of nirmatrelvir/ritonavir versus molnupiravir for COVID-19 in outpatient setting: multicenter prospective observational study

JJ Park, H Kim, YK Kim, SS Lee, E Jung… - Journal of Korean …, 2023 - ncbi.nlm.nih.gov
Background In this study, we aimed to compare the effectiveness and adverse reactions of
nirmatrelvir/ritonavir and molnupiravir in high-risk outpatients with coronavirus disease 2019 …

Remdesivir for the treatment of hospitalised patients with COVID-19: final results from the DisCoVeRy randomised, controlled, open-label trial

F Ader, M Bouscambert-Duchamp, M Hites… - Medrxiv, 2022 - medrxiv.org
Background The antiviral efficacy of remdesivir is still controversial. We aimed at evaluating
its clinical effectiveness in hospitalised patients with COVID-19, with indication of oxygen …