Introduction: Type 2 diabetes mellitus (T2DM) is a chronic disorder characterized by
persistent hyperglycemia. Chronic hyperglycemia in diabetes mellitus can cause …

Background: Insulin and apelin appears to play a range of roles in ß-cell growth and insulin
secretion and most importantly interaction with other hormonal mediators and regulators of …

Background: Adipose tissue hormones, adipokines, play an important role in diabetes
mellitus. Apelin has been added to the family of adipokines. Many risk factors can be …

Objective: To investigate blood apelin concentrations in patients with newly diagnosed and
untreated type 2 diabetes mellitus (T2DM) who had no additional disorder and to investigate …

Background Obesity causes changes in the production of adipose tissue secreted factors,
which are responsible for metabolism modulation. One of these factors is Apelin, a small …

Background The physiological role of apelin in obesity and diabetes remains unclear.
Although apelin has been studied in persons with different conditions, no studies have yet …

Type 2 diabetes mellitus (T2DM) is a metabolic disorder associated with abundant
adipocytokine changes which may play an important role in the progression of insulin …

Background Apelin is an adipokine that plays a role in the regulation of glucose
homeostasis and in obesity. The relationship between apelin serum concentration and …

Type 2 diabetes mellitus is a common type of diabetes and considered as multifactorial
disease. Apelin is an adipokine which secreted from white adipose tissue and involved in …

Background Apelin is a new adipokine that is secreted by adipocytes, and is associated with
insulin resistance (IR), inflammation, and obesity. This study was designed to investigate the …