1 School of Pharmaceutical Sciences and International Collaborative Center on Growth
Factor Research, Wenzhou Medical University, Wenzhou, China, 2 Institute of Life Sciences …

Cancer stemness is associated with high malignancy and low differentiation, as well as
therapeutic resistance of tumors including pancreatic ductal adenocarcinoma (PDAC) …

Targeting molecular descriptors of pancreatic embryogenesis may be relevant to treating
pancreatic ductal adenocarcinoma (PDAC). This strategy recognizes the cancer stem cell …

Pancreatic cancer (PC) is difficult to defeat due to mechanism (s) driving metastasis and
drug resistance. Cancer stemness is a major challenging phenomenon associated with PC …

Pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic tumor, is a
highly aggressive human cancer with the lowest five-year survival rate of any human …

The aberrant activation of the FGFR signaling is detected in many solid tumors, including
pancreatic ductal adenocarcinoma (PDAC), suggesting it as a potential therapeutic target. In …

Cancer stem cells (CSC) present a formidable clinical challenge by escaping therapeutic
intervention and seeding tumors through processes that remain incompletely understood …

Pancreas, as a vital glandular organ, is made of both endocrine tissue (which regulates
blood sugar levels) and exocrine tissue (which helps digest food). Therefore, each …

Pancreatic cancer is characterised by desmoplasia, driven by activated pancreatic stellate
cells (PSC s). Over‐expression of FGF s and their receptors is a feature of pancreatic cancer …

Pancreatic cancer is among the 3rd leading cause of cancer related deaths in the United
States along with a 5-year survival rate of 7%. The aggressive biology of the disease is …