Therapeutic interventions for disorders of fear and anxiety rely on behavioral approaches
that reduce pathological fear memories. For example, learning that threat-predictive stimuli …

The regulation of fear memories is critical for adaptive behaviors and dysregulation of these
processes is implicated in trauma-and stress-related disorders. Treatments for these …

Fear extinction, the reduction of fear by repeated exposure to the object of fear, is a crucial
paradigm of inhibitory learning and the acknowledged preclinical model for behavior …

Anxiety disorders are commonly treated with exposure-based therapies that rely on
extinction of conditioned fear. Persistent fear and anxiety following exposure therapy could …

The ability to extinguish conditioned fear memory is critical for adaptive control of fear
response, and its impairment is a hallmark of emotional disorders like post-traumatic stress …

Fear extinction is a form of inhibitory learning that allows for the adaptive control of
conditioned fear responses. Although fear extinction is an active learning process that …

Persistent anxiety after a psychological trauma is a hallmark of many anxiety disorders.
However, the neural circuits mediating the extinction of traumatic fear memories remain …

Understanding how fears are acquired is an important step in translating basic research to
the treatment of fear-related disorders. However, understanding how learned fears are …

Emotional arousal strengthens memory. This is most apparent in aversive conditioning, in
which the stress-related neurotransmitter norepinephrine (NE) enhances associations …

An issue of increasing theoretical and translational importance is to understand the
conditions under which learned fear can be suppressed, or even eliminated. Basic research …