Neutralizing and cross-reacting antibodies: implications for immunotherapy and SARS-CoV-2 vaccine development

SA Cohen, C Kellogg, O Equils - Human vaccines & …, 2021 - Taylor & Francis
The novel coronavirus SARS-CoV-2 emerged in China in 2019 and quickly spread globally,
causing a pandemic. There is an urgent need to develop vaccines against the virus, and …

Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …

Impact of ageing on homologous and human-coronavirus-reactive antibodies after SARS-CoV-2 vaccination or infection

F Zhou, J Vahokoski… - npj Vaccines, 2024 - nature.com
The endemic human coronaviruses (HCoVs) circulate worldwide yet remain understudied
and unmitigated. The observation of elevated levels of HCoV reactive antibodies in COVID …

[HTML][HTML] Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual

E Seydoux, LJ Homad, AJ MacCamy, KR Parks… - BioRxiv, 2020 - ncbi.nlm.nih.gov
B cells specific for the SARS-CoV-2 S envelope glycoprotein spike were isolated from a
COVID-19-infected subject using a stabilized spike-derived ectodomain (S2P) twenty-one …

[HTML][HTML] Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses

N Ortega, M Ribes, M Vidal, R Rubio, R Aguilar… - Nature …, 2021 - nature.com
Unraveling the long-term kinetics of antibodies to SARS-CoV-2 and the individual
characteristics influencing it, including the impact of pre-existing antibodies to human …

SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus

M Dogan, L Kozhaya, L Placek, C Gunter… - Communications …, 2021 - nature.com
Abstract Development of antibody protection during SARS-CoV-2 infection is a pressing
question for public health and for vaccine development. We developed highly sensitive …

[HTML][HTML] Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

EM Anderson, EC Goodwin, A Verma, CP Arevalo… - Cell, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread within
the human population. Although SARS-CoV-2 is a novel coronavirus, most humans had …

A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity

AT Huang, B Garcia-Carreras, MDT Hitchings… - Nature …, 2020 - nature.com
Many public health responses and modeled scenarios for COVID-19 outbreaks caused by
SARS-CoV-2 assume that infection results in an immune response that protects individuals …

Broadly-neutralizing antibodies against emerging SARS-CoV-2 variants

LB Shrestha, N Tedla, RA Bull - Frontiers in immunology, 2021 - frontiersin.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
have become a major concern in the containment of current pandemic. The variants …

[HTML][HTML] SARS-CoV-2 antibodies from children exhibit broad neutralization and belong to adult public clonotypes

SC Wall, N Suryadevara, C Kim, AR Shiakolas… - Cell Reports …, 2023 - cell.com
From the beginning of the COVID-19 pandemic, children have exhibited different
susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …