The new era of drug therapy for obesity: the evidence and the expectations

BJ Jones, SR Bloom - Drugs, 2015 - Springer
There is an urgent need for effective pharmacological therapies to help tackle the growing
obesity epidemic and the healthcare crisis it poses. The past 3 years have seen approval of …

Advances in physiology, design and development of novel medications changing the landscape of obesity pharmacotherapy

M Chakhtoura, CS Mantzoros - Metabolism-Clinical and …, 2023 - metabolismjournal.com
As the word has been celebrating innovations and technological achievements during the
last few decades, there has also been a noticeable increase in various non-communicable …

360-degree perspectives on obesity

M Cuciureanu, CC Caratașu, L Gabrielian… - Medicina, 2023 - mdpi.com
Alarming statistics show that the number of people affected by excessive weight has
surpassed 2 billion, representing approximately 30% of the world's population. The aim of …

Anti-obesity drugs: past, present and future

RJ Rodgers, MH Tschöp… - Disease models & …, 2012 - journals.biologists.com
The ideal anti-obesity drug would produce sustained weight loss with minimal side effects.
The mechanisms that regulate energy balance have substantial built-in redundancy, overlap …

Medical treatment of obesity: the past, the present and the future

GA Bray - Best practice & research Clinical gastroenterology, 2014 - Elsevier
Medications for the treatment of obesity began to appear in the late 19th and early 20th
century. Amphetamine-addiction led to the search for similar drugs without addictive …

Review of advances in anti-obesity pharmacotherapy: implications for a multimodal treatment approach with metabolic surgery

AC Sudlow, CW le Roux, DJ Pournaras - Obesity Surgery, 2019 - Springer
There is a growing need for treatments for patients who would benefit from further weight
loss following bariatric surgery or weight loss maintenance/long-term disease remission …

Latest approaches for the treatment of obesity

VM Jackson, DM Breen, JP Fortin, A Liou… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Obesity is a body weight disorder characterized by excess adiposity that
increases the risk for developing co-morbidities such as type 2 diabetes. A large medical …

[图书][B] Obesity: mechanisms and clinical management

RH Eckel - 2003 - books.google.com
Written by an international group of leading experts on obesity and related disorders, this
volume is the first to address the clinical aspects of obesity. The contributors review the latest …

Current drug targets in obesity pharmacotherapy–a review

SP Bhat, A Sharma - Current Drug Targets, 2017 - ingentaconnect.com
Obesity, an impending global pandemic, is not being effectively controlled by current
measures such as lifestyle modifications, bariatric surgery or available medications. Its toll …

Pharmacological approaches for the treatment of obesity

JA Fernández-López, X Remesar, M Foz, M Alemany - Drugs, 2002 - Springer
The high incidence of obesity, its multifactorial nature, the complexity and lack of knowledge
of the bodyweight control system, and the scarcity of adequate therapeutics have fuelled anti …