Possible application of H2S-producing compounds in therapy of coronavirus (COVID-19) infection and pneumonia

MB Evgen'ev, A Frenkel - Cell Stress and Chaperones, 2020 - Springer
Objectives Based on the above data and considerations, we suggest the application of a
harmless H2S donor (sodium thiosulfate) to treat patients at any stage of the COVID-19 virus …

Anti‐inflammatory and antiviral roles of hydrogen sulfide: Rationale for considering H2S donors in COVID‐19 therapy

V Citi, A Martelli, V Brancaleone, S Brogi… - British journal of …, 2020 - Wiley Online Library
The COVID‐19 pandemic caused by SARS‐Cov‐2 demands rapid, safe and effective
therapeutic options. In the last decades, the endogenous gasotransmitter hydrogen sulfide …

N-acetylcysteine and hydrogen sulfide in coronavirus disease 2019

AR Bourgonje, AK Offringa, LE van Eijk… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Hydrogen sulfide (H2S) is one of the three main gasotransmitters that are
endogenously produced in humans and are protective against oxidative stress. Recent …

H2S as a potential defense against COVID-19?

G Yang - American Journal of Physiology-Cell Physiology, 2020 - journals.physiology.org
The outbreak of COVID-19 pneumonia caused by a new coronavirus (severe acute
respiratory syndrome coronavirus 2, SARS-CoV-2) is posing a global health emergency and …

Use of thiols in the treatment of COVID-19: current evidence

M Cazzola, P Rogliani, SS Salvi, J Ora, MG Matera - Lung, 2021 - Springer
There is a possible role for oxidative stress, a state characterized by an altered balance
between the production of free radicals or reactive oxygen species (ROS) and antioxidant …

Serum hydrogen sulfide and outcome association in pneumonia by the SARS-CoV-2 coronavirus

G Renieris, K Katrini, C Damoulari, K Akinosoglou… - Shock, 2020 - journals.lww.com
Background: The pneumonia of COVID-19 illness has often a subtle initial presentation
making mandatory the use of biomarkers for evaluation of severity and prediction of final …

The Antiviral Roles of Hydrogen Sulfide by Blocking the Interaction between SARS‐CoV‐2 and Its Potential Cell Surface Receptors

J Dai, X Teng, S Jin, Y Wu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
The ongoing coronavirus disease 2019 (COVID‐19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is posing a great threat to the global …

N‐Acetylcysteine and Other Sulfur‐Donors as a Preventative and Adjunct Therapy for COVID‐19

HN du Preez, C Aldous, HG Kruger… - Advances in …, 2022 - Wiley Online Library
The airway epithelial glycocalyx plays an important role in preventing severe acute
respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial …

Renal consequences of the novel coronavirus disease 2019 (COVID-19) and hydrogen sulfide as a potential therapy

GJ Dugbartey, KK Alornyo, BO Ohene, V Boima… - Nitric Oxide, 2022 - Elsevier
The novel coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global
pandemic which is primarily considered a respiratory illness. However, emerging reports …

Reactive sulfur compounds in the fight against COVID-19

M Iciek, A Bilska-Wilkosz, M Kozdrowicki, M Górny - Antioxidants, 2022 - mdpi.com
The SARS-CoV-2 coronavirus pandemic outbreak in 2019 resulted in the need to search for
an effective and safe strategy for treating infected patients, relieving symptoms, and …