Identification and potential regulatory properties of Evolutionary Conserved Regions (ECRs) at the schizophrenia-associated MIR137 locus
O Gianfrancesco, D Griffiths, P Myers… - Journal of Molecular …, 2016 - Springer
Genome-wide association studies (GWAS) have identified a region at chromosome 1p21. 3,
containing the microRNA MIR137, to be among the most significant associations for …
containing the microRNA MIR137, to be among the most significant associations for …
A GWAS SNP for schizophrenia is linked to the internal MIR137 promoter and supports differential allele-specific expression
A Warburton, G Breen, VJ Bubb… - Schizophrenia …, 2016 - academic.oup.com
Single nucleotide polymorphisms (SNPs) within the MIR137 gene locus have been shown to
confer risk for schizophrenia through genome-wide association studies (GWAS). The …
confer risk for schizophrenia through genome-wide association studies (GWAS). The …
The MIR137 VNTR rs58335419 Is Associated With Cognitive Impairment in Schizophrenia and Altered Cortical Morphology
Genome-wide association studies (GWAS) of schizophrenia have strongly implicated a risk
locus in close proximity to the gene for miR-137. While there are candidate single-nucleotide …
locus in close proximity to the gene for miR-137. While there are candidate single-nucleotide …
The genome-wide supported microRNA-137 variant predicts phenotypic heterogeneity within schizophrenia
We examined the influence of the genome-wide significant schizophrenia risk variant
rs1625579 near the microRNA (miRNA)-137 (MIR137) gene on well-established sources of …
rs1625579 near the microRNA (miRNA)-137 (MIR137) gene on well-established sources of …
MIR137 polygenic risk is associated with schizophrenia and affects functional connectivity of the dorsolateral prefrontal cortex
BackgroundGenome-wide association studies (GWAS) have consistently revealed that a
variant of microRNA 137 (MIR137) shows a quite significant association with schizophrenia …
variant of microRNA 137 (MIR137) shows a quite significant association with schizophrenia …
Transcriptional targets of the schizophrenia risk gene MIR137
Genome-wide association studies (GWAS) have strongly implicated MIR137 (the gene
encoding the microRNA miR-137) in schizophrenia. A parsimonious hypothesis is that a …
encoding the microRNA miR-137) in schizophrenia. A parsimonious hypothesis is that a …
[HTML][HTML] Novel brain expressed RNA identified at the MIR137 schizophrenia-associated locus
O Gianfrancesco, A Warburton, DA Collier… - Schizophrenia …, 2017 - Elsevier
Genome-wide association studies (GWAS) have identified a locus on chromosome 1p21. 3
to be highly associated with schizophrenia. A microRNA, MIR137, within this locus has been …
to be highly associated with schizophrenia. A microRNA, MIR137, within this locus has been …
Meta gene set enrichment analyses link miR-137-regulated pathways with schizophrenia risk
Background: A single nucleotide polymorphism (SNP) within MIR137, the host gene for miR-
137, has been identified repeatedly as a risk factor for schizophrenia. Previous genetic …
137, has been identified repeatedly as a risk factor for schizophrenia. Previous genetic …
A comprehensive review of the genetic and biological evidence supports a role for MicroRNA‐137 in the etiology of schizophrenia
K Sakamoto, JJ Crowley - … Journal of Medical Genetics Part B …, 2018 - Wiley Online Library
Since it was first associated with schizophrenia (SCZ) in a 2011 genome‐wide association
study (GWAS), there have been over 100 publications focused on MIR137, the gene …
study (GWAS), there have been over 100 publications focused on MIR137, the gene …
[HTML][HTML] Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells
MIR137, transcribed as the microRNA miR-137, is one of the leading candidate
schizophrenia susceptibility genes to arise from large genome-wide association studies …
schizophrenia susceptibility genes to arise from large genome-wide association studies …