NK cells-Dr. Jekyll and Mr. Hyde in autoimmune rheumatic diseases

T Hojjatipour, S Aslani, S Salimifard, H Mikaeili… - International …, 2022 - Elsevier
Natural killer (NK) cells belong to innate immune system that are large granular lymphocytes
differentiating from the common lymphoid progenitors. These cells were first identified by …

The role of natural killer cells in autoimmune diseases

UC Kucuksezer, E Aktas Cetin, F Esen… - Frontiers in …, 2021 - frontiersin.org
Natural killer (NK) cells, the large granular lymphocytes differentiated from the common
lymphoid progenitors, were discovered in early 1970's. They are members of innate …

Natural killer cells and their role in rheumatoid arthritis: friend or foe?

H Shegarfi, F Naddafi… - The Scientific World …, 2012 - Wiley Online Library
Rheumatoid arthritis (RA) is a long‐term disease that leads to inflammation of the joints and
surrounding tissues. Natural killer (NK) cells are an important part of the innate immune …

Natural killer cells in human autoimmune disorders

LA Fogel, WM Yokoyama, AR French - Arthritis research & therapy, 2013 - Springer
Natural killer (NK) cells are innate lymphocytes that play a critical role in early host defense
against viruses. Through their cytolytic capacity and generation of cytokines and …

The role of natural killer cells in pathogenesis of autoimmune diseases

K Popko, E Górska - Central European Journal of Immunology, 2015 - termedia.pl
There is growing evidence that NK cell-mediated immunoregulation plays an important role
in the control of autoimmunity. NK cells are a subset of lymphocytes that generally contribute …

The role of Natural Killer cells in the pathogenesis of rheumatoid arthritis: major contributors or essential homeostatic modulators?

DJ Ahern, FM Brennan - Immunology letters, 2011 - Elsevier
Natural Killer (NK) cells are lymphocytes of the innate immune system, originally described
by their capacity to control tumour cells and eliminate virus-infected cells. However …

Emerging role for NK cells in the pathogenesis of inflammatory arthropathies

P Conigliaro, R Scrivo, G Valesini, R Perricone - Autoimmunity reviews, 2011 - Elsevier
Natural killer (NK) cells are large, granular lymphocytes devoted to the defense against
microbial agents and cancer cells, traditionally recognized as an important arm of the innate …

Natural killer cells in human autoimmune diseases

N Schleinitz, F Vély, JR Harlé, E Vivier - Immunology, 2010 - Wiley Online Library
Natural killer (NK) cells have been implicated in tumour surveillance and in the early control
of several microbial infections. In autoimmune disease their involvement in these processes …

Natural killer cells in inflammatory autoimmune diseases

Y Yang, J Day… - Clinical & …, 2021 - Wiley Online Library
Natural killer (NK) cells are a specialised population of innate lymphoid cells (ILCs) that help
control local immune responses. Through natural cytotoxicity, production of cytokines and …

NK cells in autoimmunity: a two-edg'd weapon of the immune system

R Perricone, C Perricone, C De Carolis… - Autoimmunity reviews, 2008 - Elsevier
Natural killer (NK) cells are part of the innate-immune system and respond rapidly to a
variety of insults via cytokine secretion and cytolytic activity. Their main function is first line of …