Rapid and continuous modulation of hippocampal network state during exploration of new places

C Kemere, MF Carr, MP Karlsson, LM Frank - PloS one, 2013 - journals.plos.org
Hippocampal information processing is often described as two-state, with a place cell state
during movement and a reactivation state during stillness. Relatively little is known about …

Spatial learning drives rapid goal representation in hippocampal ripples without place field accumulation or goal-oriented theta sequences

BE Pfeiffer - Journal of Neuroscience, 2022 - Soc Neuroscience
The hippocampus is critical for rapid acquisition of many forms of memory, although the
circuit-level mechanisms through which the hippocampus rapidly consolidates novel …

Hippocampal network dynamics constrain the time lag between pyramidal cells across modified environments

K Diba, G Buzsáki - Journal of Neuroscience, 2008 - Soc Neuroscience
The hippocampus provides a spatial map of the environment. Changes in the environment
alter the firing patterns of hippocampal neurons, but are presumably constrained by …

[HTML][HTML] Flexible rerouting of hippocampal replay sequences around changing barriers in the absence of global place field remapping

J Widloski, DJ Foster - Neuron, 2022 - cell.com
Flexibility is a hallmark of memories that depend on the hippocampus. For navigating
animals, flexibility is necessitated by environmental changes such as blocked paths and …

Intracellular determinants of hippocampal CA1 place and silent cell activity in a novel environment

J Epsztein, M Brecht, AK Lee - Neuron, 2011 - cell.com
For each environment a rodent has explored, its hippocampus contains a map consisting of
a unique subset of neurons, called place cells, that have spatially tuned spiking there, with …

Experience-dependent shaping of hippocampal CA1 intracellular activity in novel and familiar environments

JD Cohen, M Bolstad, AK Lee - Elife, 2017 - elifesciences.org
The hippocampus is critical for producing stable representations of familiar spaces. How
these representations arise is poorly understood, largely because changes to hippocampal …

[HTML][HTML] New experiences enhance coordinated neural activity in the hippocampus

S Cheng, LM Frank - Neuron, 2008 - cell.com
The acquisition of new memories for places and events requires synaptic plasticity in the
hippocampus, and plasticity depends on temporal coordination among neurons. Spatial …

Memory modulates journey-dependent coding in the rat hippocampus

J Ferbinteanu, P Shirvalkar… - Journal of Neuroscience, 2011 - Soc Neuroscience
Neurons in the rat hippocampus signal current location by firing in restricted areas called
place fields. During goal-directed tasks in mazes, place fields can also encode past and …

Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex

A Chenani, M Sabariego, MI Schlesiger… - Nature …, 2019 - nature.com
The hippocampus is an essential brain area for learning and memory. However, the network
mechanisms underlying memory storage, consolidation and retrieval remain incompletely …

[HTML][HTML] Signatures of rapid plasticity in hippocampal CA1 representations during novel experiences

JB Priestley, JC Bowler, SV Rolotti, S Fusi, A Losonczy - Neuron, 2022 - cell.com
Neurons in the hippocampus exhibit a striking selectivity for specific combinations of sensory
features, forming representations that are thought to subserve episodic memory. Even …