The role of adaptive T cell immunity in atherosclerosis

Z Mallat, S Taleb, H Ait-Oufella, A Tedgui - Journal of lipid research, 2009 - ASBMB
There is now solid evidence that T cell adaptive immunity is involved in atherogenesis.
While initial studies have focused on the pathogenic arm of the immune response, more …

Regulatory T cells in atherosclerosis and strategies to induce the endogenous atheroprotective immune response

DA Chistiakov, IA Sobenin, AN Orekhov - Immunology Letters, 2013 - Elsevier
Atherosclerosis is a chronic inflammatory disease, in which multiple types of immune cells
are involved. Th1 and Th17 cells play a prominent role in induction and progression of local …

Atherosclerosis: a classic inflammatory disease

A Anogeianaki, D Angelucci… - International …, 2011 - journals.sagepub.com
Atherosclerosis is an inflammatory disease due to a diet high in saturated fat,
hypercholesterolemia, obesity, hypoglycemia, etc. mainly mediated by the infiltration of …

Advances in immunotherapy modalities for atherosclerosis

Q Meng, H Liu, J Liu, Y Pang, Q Liu - Frontiers in Pharmacology, 2023 - frontiersin.org
Cardiovascular disease (CVD) is one of the leading causes of death worldwide.
Atherosclerosis is the pathological basis of atherosclerotic cardiovascular disease (ASCVD) …

The B cell: a good guy in vascular disease?

GK Hansson - Arteriosclerosis, thrombosis, and vascular biology, 2002 - Am Heart Assoc
Inflammatory cells and molecules have largely been considered bad guys in the
pathogenesis of atherosclerosis and other vascular diseases. This is particularly true for …

Identification of potential therapeutic targets for atherosclerosis by analysing the gene signature related to different immune cells and immune regulators in …

Y Shen, L Xu, X Tang, C Lin, D Yan, S Xue… - BMC Medical …, 2021 - Springer
Background Atherosclerosis is a chronic inflammatory disease that affects multiple arteries.
Numerous studies have shown the inherent immune diversity in atheromatous plaques and …

[PDF][PDF] Atherosclerosis: immunopathogenesis and immunotherapy

R Ohashi, H Mu, C Chen - Medical Science Monitor, 2004 - researchgate.net
Atherosclerosis is a chronic disease that causes various cardiovascular complications.
Although the initiation and progression of atherosclerosis largely depend on genetic factors …

Regulatory T-cell immunity in atherosclerosis

Z Mallat, H Ait-Oufella, A Tedgui - Trends in Cardiovascular Medicine, 2007 - Elsevier
Atherosclerosis is an inflammatory disease of the arterial wall where both innate and
adaptive T-cell-driven immunoinflammatory responses contribute to disease development …

Impact of immunity on coronary artery disease: an updated pathogenic interplay and potential therapeutic strategies

N Laera, P Malerba, G Vacanti, S Nardin, M Pagnesi… - Life, 2023 - mdpi.com
Coronary artery disease (CAD) is the leading cause of death worldwide. It is a result of the
buildup of atherosclerosis within the coronary arteries. The role of the immune system in …

CD8+ T Cells in Atherosclerosis

S Schäfer, A Zernecke - Cells, 2020 - mdpi.com
Atherosclerotic lesions are populated by cells of the innate and adaptive immune system,
including CD8+ T cells. The CD8+ T cell infiltrate has recently been characterized in mouse …