Decidual natural killer (NK) cells are thought to play a significant role in the allorecognition
mechanisms during pregnancy. Through their activating and inhibitory receptors they may …

Both HLA class I molecules and their receptors on Natural Killer cells, the KIR molecules,
are highly polymorphic. It is generally believed that this variation is driven in response to the …

The establishment of the human placenta in early pregnancy is characterized by the
presence of large numbers of natural killer (NK) cells within the maternal decidua in close …

Immunogenetic studies suggest that interactions between maternal killer Ig-like receptor
(KIR) expressed by uterine NK (uNK) cells, and fetal HLA-C molecules on trophoblast …

Many common disorders of pregnancy are attributed to insufficient invasion of the uterine
lining by trophoblast, fetal cells that are the major cell type of the placenta. Interactions …

The major leukocyte population in the decidua during the first trimester of pregnancy
consists of NK cells that express receptors capable of recognizing MHC class I molecules …

The expression of natural killer (NK) cell receptors specific for HLA class I molecules has
been studied in CD56bright, CD3− NK cells isolated from the pregnant uterine mucosa, the …

Pregnancy is a unique immunological situation in which a fetus-bearing paternal
histocompatibility antigens can survive in a maternal environment without apparent …

Large numbers of natural killer cells are present within the maternal decidua close to the
extravillous trophoblast cells. Most of these natural killer cells express high levels of …

Large numbers of decidual natural killer (dNK) cells are in direct contact with the invading
trophoblast and are considered to be important for pregnancy, since they can produce …