[HTML][HTML] A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model

J Kreye, SM Reincke, HC Kornau, E Sánchez-Sendin… - bioRxiv - ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019
(COVID-19), manifesting with respiratory symptoms and multi-organ dysfunction. Detailed …

[HTML][HTML] A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model

J Kreye, SM Reincke, HC Kornau, E Sánchez-Sendin… - Cell, 2020 - cell.com
The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019
(COVID-19), manifesting with respiratory symptoms and multi-organ dysfunction. Detailed …

Isolating multiple formats of human monoclonal neutralizing antibodies against SARS-CoV-2 by in vitro site-directed antibody screening

X Liu, F Gao, L Gou, Y Chen, Y Gu, L Ao, H Shen, Z Hu… - bioRxiv, 2020 - biorxiv.org
Neutralizing antibody is one of the most effective interventions for acute pathogenic
infection. Currently, over three million people have been identified for SARS-CoV-2 infection …

Fc-modified SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models

M Takeshita, H Fukuyama, K Kamada, T Matsumoto… - bioRxiv, 2022 - biorxiv.org
The use of therapeutic neutralizing antibodies against SARS-CoV-2 infection has been
highly effective. However, there remain few practical antibodies against viruses that are …

Rapid selection of a human monoclonal antibody that potently neutralizes SARS-CoV-2 in two animal models

W Li, A Drelich, DR Martinez, L Gralinski, C Chen… - BioRxiv, 2020 - biorxiv.org
Effective therapies are urgently needed for the SARS-CoV-2/COVID19 pandemic. We
identified panels of fully human monoclonal antibodies (mAbs) from eight large phage …

Potent mouse monoclonal antibodies that block SARS-CoV-2 infection

Y Guo, A Kawaguchi, M Takeshita, T Sekiya… - Journal of Biological …, 2021 - ASBMB
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has developed into a global pandemic since its first outbreak …

A potent SARS-CoV-2 neutralizing human monoclonal antibody that reduces viral burden and disease severity in Syrian hamsters

AC Fagre, J Manhard, R Adams, M Eckley… - Frontiers in …, 2020 - frontiersin.org
The emergence of COVID-19 has led to a pandemic that has caused millions of cases of
disease, variable morbidity and hundreds of thousands of deaths. Currently, only remdesivir …

Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model

M Imbrechts, W Maes, L Ampofo, N Van den Berghe… - Iscience, 2022 - cell.com
Treatment with neutralizing monoclonal antibodies (mAbs) against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) contributes to COVID-19 management …

Structurally resolved SARS-CoV-2 antibody shows high efficacy in severely infected hamsters and provides a potent cocktail pairing strategy

S Du, Y Cao, Q Zhu, P Yu, F Qi, G Wang, X Du, L Bao… - Cell, 2020 - cell.com
Understanding how potent neutralizing antibodies (NAbs) inhibit SARS-CoV-2 is critical for
effective therapeutic development. We previously described BD-368-2, a SARS-CoV-2 NAb …

[PDF][PDF] Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody

W Li, A Drelich, DR Martinez, L Gralinski, C Chen… - BioRxiv, 2020 - researchgate.net
Effective therapies are urgently needed for the SARS-CoV-2/COVID19 pandemic. We
identified panels of fully human monoclonal antibodies (mAbs) from eight large …