Single particle automated Raman trapping analysis of breast cancer cell-derived extracellular vesicles as cancer biomarkers

J Penders, A Nagelkerke, EM Cunnane, SV Pedersen… - ACS …, 2021 - ACS Publications
Extracellular vesicles (EVs) secreted by cancer cells provide an important insight into cancer
biology and could be leveraged to enhance diagnostics and disease monitoring. This paper …

Enabling sensitive phenotypic profiling of cancer-derived small extracellular vesicles using surface-enhanced Raman spectroscopy nanotags

W Zhang, L Jiang, RJ Diefenbach, DH Campbell… - ACS …, 2020 - ACS Publications
Circulating cancer-derived small extracellular vesicles (EVs) are nanoscale membranous
vesicles shed from cancer cells that are released into surrounding body fluids. Small EVs …

Label-free prostate cancer detection by characterization of extracellular vesicles using raman spectroscopy

W Lee, A Nanou, L Rikkert, FAW Coumans… - Analytical …, 2018 - ACS Publications
Mammalian cells release extracellular vesicles (EVs) into their microenvironment that travel
the entire body along the stream of bodily fluids. EVs contain a wide range of biomolecules …

MoS2-Plasmonic Nanocavities for Raman Spectra of Single Extracellular Vesicles Reveal Molecular Progression in Glioblastoma

M Jalali, C del Real Mata, L Montermini, O Jeanne… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are continually released from cancer cells into biofluids, carrying
actionable molecular fingerprints of the underlying disease with considerable diagnostic and …

Label‐Free Identification of Exosomes using Raman Spectroscopy and Machine Learning

U Parlatan, MO Ozen, I Kecoglu, B Koyuncu, H Torun… - Small, 2023 - Wiley Online Library
Exosomes, nano‐sized extracellular vesicles (EVs) secreted from cells, carry various cargo
molecules reflecting their cells of origin. As EV content, structure, and size are highly …

Surface enhanced Raman scattering of extracellular vesicles for cancer diagnostics despite isolation dependent lipoprotein contamination

HJ Koster, T Rojalin, A Powell, D Pham, RR Mizenko… - Nanoscale, 2021 - pubs.rsc.org
Given the emerging diagnostic utility of extracellular vesicles (EVs), it is important to account
for non-EV contaminants. Lipoprotein present in EV-enriched isolates may inflate particle …

Emerging integrated SERS-microfluidic devices for analysis of cancer-derived small extracellular vesicles

L Ngo, A Tukova, A Hassanzadeh-Barforoushi… - Lab on a Chip, 2023 - pubs.rsc.org
Cancer-derived small extracellular vesicles (sEVs) are specific subgroups of lipid bilayer
vesicles secreted from cancer cells to the extracellular environment. They carry distinct …

A specific spectral signature of serum and plasma-derived extracellular vesicles for cancer screening

C Krafft, K Wilhelm, A Eremin, S Nestel… - … , Biology and Medicine, 2017 - Elsevier
In cancer, extracellular vesicles (EV) contribute to tumor progression by regulating local and
systemic effects. Being released into body fluids, EV may be used in nanomedicine as a …

Artificial intelligent label-free SERS profiling of serum exosomes for breast cancer diagnosis and postoperative assessment

Y Xie, X Su, Y Wen, C Zheng, M Li - Nano letters, 2022 - ACS Publications
Breast cancer subtypes have important implications of treatment responses and clinical
outcomes. Exosomes have been considered as promising biomarkers for liquid biopsies, but …

Multifunctional detection of extracellular vesicles with surface plasmon resonance microscopy

Y Yang, C Zhai, Q Zeng, AL Khan, H Yu - Analytical Chemistry, 2020 - ACS Publications
Extracellular vesicles (EVs), including exosomes, are promising circulating biomarkers for
disease diagnosis. Conventional EVs analysis requires multiple instrumentations to obtain …