An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis
Y Liu, D Chen, J Hou, H Li, D Cao, M Guo, Y Ling… - Cytokine, 2021 - Elsevier
The hyper-inflammatory response is thought to be a major cause of acute respiratory
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …
The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …
The signal pathways and treatment of cytokine storm in COVID-19
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …
and is more devastating than any other previous infectious disease. It has affected a …
The dynamic changes in cytokine responses in COVID-19: a snapshot of the current state of knowledge
M Buszko, JH Park, D Verthelyi, R Sen, HA Young… - Nature …, 2020 - nature.com
“The role of cytokines in COVID-19” online symposium was presented on 18 June 2020 by
the NIH/FDA Immunology and Cytokine Interest Groups and was purposed to discuss our …
the NIH/FDA Immunology and Cytokine Interest Groups and was purposed to discuss our …
Severe COVID-19 is characterized by the co-occurrence of moderate cytokine inflammation and severe monocyte dysregulation
B Bonnet, J Cosme, C Dupuis, E Coupez, M Adda… - …, 2021 - thelancet.com
Background SARS-CoV-2 has been responsible for considerable mortality worldwide, owing
in particular to pulmonary failures such as ARDS, but also to other visceral failures and …
in particular to pulmonary failures such as ARDS, but also to other visceral failures and …
[HTML][HTML] Major alterations to monocyte and dendritic cell subsets lasting more than 6 months after hospitalization for COVID-19
Introduction After more than two years the Coronavirus disease-19 (COVID-19) pandemic
continues to burden healthcare systems and economies worldwide, and it is evident that the …
continues to burden healthcare systems and economies worldwide, and it is evident that the …
Monocytes and macrophages, targets of severe acute respiratory syndrome coronavirus 2: the clue for coronavirus disease 2019 immunoparalysis
Abstract Background Coronavirus disease 2019 (COVID-19) clinical expression is
pleiomorphic, severity is related to age and comorbidities such as diabetes and …
pleiomorphic, severity is related to age and comorbidities such as diabetes and …
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses
SARS-CoV-2 causes a spectrum of COVID-19 disease, the immunological basis of which
remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or …
remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or …
The role of biomarkers in diagnosis of COVID-19–A systematic review
M Kermali, RK Khalsa, K Pillai, Z Ismail, A Harky - Life sciences, 2020 - Elsevier
Aims As of the 28th April 2020, the COVID-19 pandemic has infiltrated over 200 countries
and affected over three million confirmed people. We review different biomarkers to evaluate …
and affected over three million confirmed people. We review different biomarkers to evaluate …
[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections
KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
COVID-19–associated morbidity and mortality have been attributed to a pathologic host
response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine …
response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine …