Host immune response and immunobiology of human SARS-CoV-2 infection

S Kumar, R Nyodu, VK Maurya, SK Saxena - Coronavirus Disease 2019 …, 2020 - Springer
One of the most serious viral outbreaks of the decade, infecting humans, originated from the
city of Wuhan, China, by the end of December 2019, has left the world shaken up. It is the …

[HTML][HTML] Lessons learned to date on COVID-19 hyperinflammatory syndrome: considerations for interventions to mitigate SARS-CoV-2 viral infection and detrimental …

M Cardone, M Yano, AS Rosenberg… - Frontiers in …, 2020 - frontiersin.org
The first case of human transmission of SARS-CoV-2 was reported in China in December
2019. A few months later, this viral infection had spread worldwide and became a pandemic …

Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents

S Khadke, N Ahmed, N Ahmed, R Ratts, S Raju… - Virology journal, 2020 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) is caused by Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, previously named 2019-nCov), a novel …

[HTML][HTML] Overview: systemic inflammatory response derived from lung injury caused by SARS-CoV-2 infection explains severe outcomes in COVID-19

RB Polidoro, RS Hagan, R de Santis Santiago… - Frontiers in …, 2020 - frontiersin.org
Most SARS-CoV2 infections will not develop into severe COVID-19. However, in some
patients, lung infection leads to the activation of alveolar macrophages and lung epithelial …

Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective

C Lee, WJ Choi - Archives of pharmacal research, 2021 - Springer
The novel beta coronavirus (SARS-CoV-2, designated as COVID-19) that is responsible for
severe acute respiratory syndrome has devastated the global economy and health care …

Understanding COVID-19 pandemic: molecular mechanisms and potential therapeutic strategies. An evidence-based review

R Hanna, S Dalvi, T Sălăgean, ID Pop… - Journal of …, 2021 - Taylor & Francis
Abstract Initially, the SARS-CoV-2 virus was considered as a pneumonia virus; however, a
series of peer reviewed medical papers published in the last eight months suggest that this …

[HTML][HTML] Immune Response and COVID-19: A mirror image of Sepsis

E López-Collazo, J Avendano-Ortiz… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 virus and its associated disease COVID-19 have triggered
significant threats to public health, in addition to political and social changes. An important …

Association of COVID-19 with comorbidities: an update

S Chatterjee, LV Nalla, M Sharma… - ACS Pharmacology & …, 2023 - ACS Publications
Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome-
coronavirus-2 (SARS-CoV-2) which was identified in Wuhan, China in December 2019 and …

[HTML][HTML] Hazards of the cytokine storm and cytokine-targeted therapy in patients with COVID-19

M Quirch, J Lee, S Rehman - Journal of medical Internet research, 2020 - jmir.org
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
challenged medicine and health care on a global scale. Its impact and frightening mortality …

The role of dysregulated immune responses in COVID-19 pathogenesis

S Tahaghoghi-Hajghorbani, P Zafari, E Masoumi… - Virus research, 2020 - Elsevier
Abstract The coronavirus disease-2019 (COVID-19) which caused by severe acute
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …