Infectious diseases are a major cause of death worldwide. A serious complication of
infections is septic shock. Septic shock is a critical syndrome associated with the host …

Sepsis and septic shock are among the leading causes of death in intensive care units
worldwide. Numerous studies on their pathophysiology have revealed an imbalance in the …

Despite often knowing the aetiology of sepsis and its clinical course there has not been the
anticipated advances in treatment strategies. Cytokines are influential mediators of …

Sepsis, which is a highly heterogeneous syndrome, can result in death as a consequence of
a systemic inflammatory response syndrome. The activation and regulation of the immune …

Sepsis is a devastating and complex syndrome and continues to be a major cause of
morbidity and mortality among critically ill patients at the surgical intensive care unit setting …

Background: Sepsis is a deadly immunological disorder and its pathophysiology is still
poorly understood. We aimed to determine if specific pro-inflammatory and anti-inflammatory …

Background: Sepsis is a serious clinical condition characterized by damage to the immune
system as a result of an uncontrolled response to infection. Septic patients show …

The pathophysiology of sepsis is not completely understood. Bacteria are the main cause of
sepsis. Activated receptors of the innate immune system lead to an exaggerated immune …

The appearance of detectable pro-as well as anti-inflammatory cytokines in the blood stream
during sepsis is indicative of their exacerbated production. While pro-inflammatory cytokines …

Background: Sepsis, a systemic inflammatory response to infection, resulting in organ failure
and death. Pathogenic microbial agents trigger cascades of events in sepsis by stimulating …