Reactive oxygen species in cancer biology and anticancer therapy

Y Yang, S Karakhanova, J Werner… - Current medicinal …, 2013 - ingentaconnect.com
Reactive oxygen species (ROS) are a group of highly reactive chemicals under tight control
of intracellular antioxidants. The balance in oxidation-antioxidation is essential for …

The two faces of reactive oxygen species in cancer

CR Reczek, NS Chandel - Annual review of cancer biology, 2017 - annualreviews.org
Reactive oxygen species (ROS), now appreciated for their cellular signaling capabilities,
have a dual role in cancer. On the one hand, ROS can promote protumorigenic signaling …

[HTML][HTML] Reactive oxygen species in cancer biology and anticancer therapy

AV Bazhin, PP Philippov… - Oxidative Medicine and …, 2016 - ncbi.nlm.nih.gov
Our understanding of reactive oxygen species (ROS)—a group of highly reactive chemicals
containing oxygen—has changed in the last few years from ROS as just harmful substances …

Reactive oxygen species in cancer

GY Liou, P Storz - Free radical research, 2010 - Taylor & Francis
Elevated rates of reactive oxygen species (ROS) have been detected in almost all cancers,
where they promote many aspects of tumour development and progression. However …

[HTML][HTML] The double-edged roles of ROS in cancer prevention and therapy

Y Wang, H Qi, Y Liu, C Duan, X Liu, T Xia, D Chen… - Theranostics, 2021 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) serve as cell signaling molecules generated in oxidative
metabolism and are associated with a number of human diseases. The reprogramming of …

Molecular pathways: reactive oxygen species homeostasis in cancer cells and implications for cancer therapy

V Nogueira, N Hay - Clinical Cancer Research, 2013 - AACR
Reactive oxygen species (ROS) are important in regulating normal cellular processes, but
deregulated ROS contribute to the development of various human diseases, including …

Targeting antioxidants for cancer therapy

A Glasauer, NS Chandel - Biochemical pharmacology, 2014 - Elsevier
Cancer cells are characterized by an increase in the rate of reactive oxygen species (ROS)
production and an altered redox environment compared to normal cells. Furthermore, redox …

Understanding of ROS‐inducing strategy in anticancer therapy

SJ Kim, HS Kim, YR Seo - Oxidative medicine and cellular …, 2019 - Wiley Online Library
Redox homeostasis is essential for the maintenance of diverse cellular processes. Cancer
cells have higher levels of reactive oxygen species (ROS) than normal cells as a result of …

ROS signalling in the biology of cancer

JN Moloney, TG Cotter - Seminars in cell & developmental biology, 2018 - Elsevier
Increased reactive oxygen species (ROS) production has been detected in various cancers
and has been shown to have several roles, for example, they can activate pro-tumourigenic …

Reactive oxygen species: the achilles' heel of cancer cells?

X Cui - Antioxidants & redox signaling, 2012 - liebertpub.com
Cancer development, progression, and metastasis are multistep processes. Accumulating
evidence suggests that reactive oxygen species (ROS) are critically involved in cancer cell …