Transitions in gene regulatory processes responsible for the emergence of specialized cell
types and spatiotemporal regulation of developmental signaling prior to the divergence of …

The epithelial and interstitial stem cells of the freshwater polyp Hydra are the best
characterized stem cell systems in any cnidarian, providing valuable insight into cell type …

The epithelial and interstitial stem cells of the freshwater polyp Hydra are the best-
characterized stem cell systems in any cnidarian, providing valuable insight into cell type …

Numerous developmental control genes have been isolated in a variety of organisms by
either homology cloning or system-specific strategies. Functional genetic tests, however, are …

The cnidarian model organism Hydra has long been studied for its remarkable ability to
regenerate its head, which is controlled by a head organizer located near the hypostome …

The cnidarian model organism Hydra has long been studied for its remarkable ability to
regenerate its head, which is controlled by a head organizer located near the hypostome …

Superficially, it might seem that Hydra has a rather chequered history as an experimental
subject. During the scramble to find new animal model systems in the 1960s and '70s, this …

Developmental processes in multicellular animals depend on an array of signal transduction
pathways. Studies of model organisms have identified a number of such pathways and …

INTRODUCTION The cnidarian polyp Hydra undergoes continual self-renewal and is
capable of whole-body regeneration from a small piece of tissue. The stem cell populations …

Little is known about stem cells in organisms at the beginning of evolution. To characterize
the regulatory events that control stem cells in the basal metazoan Hydra, we have …