Hyperhomocysteinemia and venous thrombosis: a meta-analysis

M Den Heijer, FR Rosendaal, HJ Blom… - Thrombosis and …, 1998 - thieme-connect.com
Hyperhomocysteinemia is an established risk factor for atherosclerosis and vascular
disease. Until the early nineties the relationship with venous thrombosis was controversial …

Hyperhomocysteinemia as a risk factor for deep-vein thrombosis

M Den Heijer, T Koster, HJ Blom… - New England journal …, 1996 - Mass Medical Soc
Background Previous studies have suggested that hyperhomocysteinemia may be a risk
factor for venous thrombosis. To assess the risk of venous thrombosis associated with …

Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease

JG Ray - Archives of internal medicine, 1998 - jamanetwork.com
Background Elevated plasma homocysteine (Hcy) levels are implicated in the development
of atherosclerotic and venous thromboembolic disease. A meta-analysis of the risk for …

Plasma homocysteine levels in patients with deep venous thrombosis

T Amundsen, PM Ueland, A Waage - … , thrombosis, and vascular …, 1995 - Am Heart Assoc
Increased risk of arterial and venous thromboembolic disease is well documented in the
homocystinuric patient. There is growing evidence that hyperhomocysteinemia is an …

Homocysteine and thrombosis: from basic science to clinical evidence

A Undas, J Brożek, A Szczeklik - Thrombosis and haemostasis, 2005 - thieme-connect.com
Homocysteine is a sulfhydryl-containing amino acid formed during the metabolism of
methionine. Rapidly accumulating evidence links elevated homocysteine levels to …

Mild hyperhomocysteinemia is an independent risk factor of arterial vascular disease

GHJ Boers - Seminars in thrombosis and hemostasis, 2000 - thieme-connect.com
Evidence of a positive association between mild hyperhomocysteinemia and arterial
vascular disease has been accumulating in the last decade. Mild hyperhomocysteinemia …

Vitamin supplementation reduces blood homocysteine levels: a controlled trial in patients with venous thrombosis and healthy volunteers

M Den Heijer, IA Brouwer, GMJ Bos… - … , and vascular biology, 1998 - Am Heart Assoc
Hyperhomocysteinemia is a risk factor for atherosclerosis and thrombosis and is inversely
related to plasma folate and vitamin B12 levels. We assessed the effects of vitamin …

Hyperhomocysteinemia and venous thromboembolism

M Cattaneo - Seminars in thrombosis and hemostasis, 2006 - thieme-connect.com
Homocysteine (Hcy) is a sulfhydryl amino acid derived from the metabolic conversion of
methionine, which is dependent on vitamins (folic acid, B 12 and B 6) as cofactors or …

Hyperhomocysteinemia, atherosclerosis and thrombosis

M Cattaneo - Thrombosis and haemostasis, 1999 - thieme-connect.com
High plasma levels of homocysteine are the results of the interplay between congenital and
environmental factors. In the last two decades, a growing amount of interest has focused on …

Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: a randomized, placebo-controlled, double …

M Den Heijer, HPJ Willems, HJ Blom, WBJ Gerrits… - Blood, 2007 - ashpublications.org
Abstract The Vitamins and Thrombosis (VITRO) study investigated the effect of
homocysteine lowering by daily supplementation of B vitamins on the risk reduction of deep …