Mammary development in the embryo and adult: a journey of morphogenesis and commitment

CJ Watson, WT Khaled - 2008 - journals.biologists.com
Mammary gland development occurs through distinctive stages throughout embryonic and
pubertal development and reproductive life. At each stage, different signals are required to …

Mammary gland development: cell fate specification, stem cells and the microenvironment

JL Inman, C Robertson, JD Mott, MJ Bissell - Development, 2015 - journals.biologists.com
The development of the mammary gland is unique: the final stages of development occur
postnatally at puberty under the influence of hormonal cues. Furthermore, during the life of …

Mammary gland development

H Macias, L Hinck - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
The mammary gland develops through several distinct stages. The first transpires in the
embryo as the ectoderm forms a mammary line that resolves into placodes. Regulated by …

Embryonic mammary gland development

E Spina, P Cowin - Seminars in cell & developmental biology, 2021 - Elsevier
Embryonic mammary gland development involves the formation of mammary placodes,
invagination of flask-shaped mammary buds and development of miniature bi-layered ductal …

[HTML][HTML] The molecular basis of mammary gland development and epithelial differentiation

PF Slepicka, AVH Somasundara… - Seminars in cell & …, 2021 - Elsevier
Our understanding of the molecular events underpinning the development of mammalian
organ systems has been increasing rapidly in recent years. With the advent of new and …

Mammary stem cells and the differentiation hierarchy: current status and perspectives

JE Visvader, J Stingl - Genes & development, 2014 - genesdev.cshlp.org
The mammary epithelium is highly responsive to local and systemic signals, which
orchestrate morphogenesis of the ductal tree during puberty and pregnancy. Based on …

Mammary development in the embryo and adult: new insights into the journey of morphogenesis and commitment

CJ Watson, WT Khaled - Development, 2020 - journals.biologists.com
The mammary gland is a unique tissue and the defining feature of the class Mammalia. It is a
late-evolving epidermal appendage that has the primary function of providing nutrition for …

Signalling pathways implicated in early mammary gland morphogenesis and breast cancer

B Howard, A Ashworth - PLoS genetics, 2006 - journals.plos.org
Specification of mammary epithelial cell fate occurs during embryogenesis as cells
aggregate to form the mammary anlage. Within the embryonic mammary bud, a population …

[HTML][HTML] Stem cells and the differentiation hierarchy in mammary gland development

NY Fu, E Nolan, GJ Lindeman… - Physiological …, 2020 - journals.physiology.org
The mammary gland is a highly dynamic organ that undergoes profound changes within its
epithelium during puberty and the reproductive cycle. These changes are fueled by …

Molecular regulators of pubertal mammary gland development

S McNally, F Martin - Annals of medicine, 2011 - Taylor & Francis
The pubertal mammary gland is an ideal model for experimental morphogenesis. The
primary glandular branching morphogenesis occurs at this time, integrating epithelial cell …