Extrapulmonary manifestations of COVID-19
A Gupta, MV Madhavan, K Sehgal, N Nair… - Nature medicine, 2020 - nature.com
Although COVID-19 is most well known for causing substantial respiratory pathology, it can
also result in several extrapulmonary manifestations. These conditions include thrombotic …
also result in several extrapulmonary manifestations. These conditions include thrombotic …
Pathogenesis of multiple organ injury in COVID-19 and potential therapeutic strategies
Severe acute respiratory disease coronavirus 2 (SARS-CoV-2, formerly 2019-nCoV) is a
novel coronavirus that has rapidly disseminated worldwide, causing the coronavirus disease …
novel coronavirus that has rapidly disseminated worldwide, causing the coronavirus disease …
Recombinant ACE2 expression is required for SARS-CoV-2 to infect primary human endothelial cells and induce inflammatory and procoagulative responses
J Nascimento Conde, WR Schutt, EE Gorbunova… - MBio, 2020 - Am Soc Microbiol
ABSTRACT SARS-CoV-2 causes COVID-19, an acute respiratory distress syndrome
(ARDS) characterized by pulmonary edema, viral pneumonia, multiorgan dysfunction …
(ARDS) characterized by pulmonary edema, viral pneumonia, multiorgan dysfunction …
[HTML][HTML] COVID-19 as a viral functional ACE2 deficiency disorder with ACE2 related multi-organ disease
R Gan, NP Rosoman, DJE Henshaw, EP Noble… - Medical hypotheses, 2020 - Elsevier
Abstract SARS-CoV-2, the agent of COVID-19, shares a lineage with SARS-CoV-1, and a
common fatal pulmonary profile but with striking differences in presentation, clinical course …
common fatal pulmonary profile but with striking differences in presentation, clinical course …
Manipulation of ACE2 expression in COVID-19
F Chaudhry, S Lavandero, X Xie, B Sabharwal… - Open …, 2020 - openheart.bmj.com
SARS-CoV-2 is the virus responsible for the ongoing COVID-19 outbreak. The virus uses
ACE2 receptor for viral entry. ACE2 is part of the counter-regulatory renin-angiotensin …
ACE2 receptor for viral entry. ACE2 is part of the counter-regulatory renin-angiotensin …
Interferon-alpha or-beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2
Severe viral pneumonia caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is characterized by a hyperinflammatory state typified by elevated circulating …
(SARS-CoV-2) is characterized by a hyperinflammatory state typified by elevated circulating …
Inflammation triggered by SARS-CoV-2 and ACE2 augment drives multiple organ failure of severe COVID-19: molecular mechanisms and implications
The widespread occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19). The S spike protein …
CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19). The S spike protein …
Angiotensin-converting enzyme 2 (ACE2): COVID 19 gate way to multiple organ failure syndromes
Background Globally, the current medical emergency for novel coronavirus 2019 (COVID-
19) leads to respiratory distress syndrome and death. Purpose This review highlighted the …
19) leads to respiratory distress syndrome and death. Purpose This review highlighted the …
The COVID-19 pandemic: a global health crisis
CA Pollard, MP Morran… - Physiological …, 2020 - journals.physiology.org
The novel coronavirus SARS-CoV-2 was identified as the causative agent for a series of
atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019 …
atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019 …
Endothelium infection and dysregulation by SARS-CoV-2: evidence and caveats in COVID-19
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …