Genome-wide association studies (GWAS) have become a preferred method to identify new genetic susceptibility loci. This technique aims to understanding the molecular etiology of …
J Yang, T Lee, J Kim, MC Cho, BG Han, JY Lee… - PLoS …, 2013 - journals.plos.org
Recent studies in population of European ancestry have shown that 30%∼ 50% of heritability for human complex traits such as height and body mass index, and common …
S Myles, D Davison, J Barrett, M Stoneking… - BMC medical …, 2008 - Springer
Background Recent genome-wide association (GWA) studies have provided compelling evidence of association between genetic variants and common complex diseases. These …
K Nam, J Kim, S Lee - Cell Genomics, 2022 - cell.com
Genome-wide association studies (GWAS) on diverse ancestry groups are lacking, resulting in deficits of genetic discoveries and polygenic scores. We conducted GWAS for 76 …
Despite the recent explosive rise in number of genetic markers for complex disease traits identified in genome-wide association studies, there is still a large gap between the known …
Genome‐wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNP s) associated with complex traits. However, the genetic heritability of …
To facilitate broad and convenient integrative visualization of and access to GWAS data, we have created the GWAS Central resource (http://www. gwascentral. org). This database …
A Koike, N Nishida, I Inoue, S Tsuji… - Journal of human …, 2009 - nature.com
The establishment of high-throughput single-nucleotide polymorphism (SNP)-typing technologies has enabled astonishing progress to be made in genome-wide association …
Polygenic scores (PGS) have been widely used to predict disease risk using variants identified from genome-wide association studies (GWAS). To date, most GWAS have been …